Patents by Inventor Mohammad Jafari
Mohammad Jafari has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11737868Abstract: A handle for a prosthetic heart valve delivery apparatus includes a housing, a motorized mechanism, and a holding mechanism. The housing is configured to be hand-held by a user and includes a distal opening. The motorized mechanism is disposed within the housing and is configured to be releasably coupled to a proximal end portion of a first shaft of the prosthetic heart valve delivery apparatus. When actuated, the motorized mechanism is configured to rotate the first shaft relative to the housing. The holding mechanism is disposed inside the housing and is configured to engage a proximal end portion of a second shaft of the prosthetic heart valve delivery apparatus such that the second shaft is axially and rotationally fixed relative to the housing, and the first shaft extends through the second shaft.Type: GrantFiled: February 5, 2020Date of Patent: August 29, 2023Assignee: EDWARDS LIFESCIENCES CORPORATIONInventors: Michael J. Popp, David Alon, Jun Liu, Luca Pesce, Mohammad Jafari
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Publication number: 20220226110Abstract: An expandable docking station includes an annular valve seat having an end, an annular outer wall comprising struts disposed around the valve seat, and links that connect the end of the annular valve seat to the annular outer wall. Each of the links extends from the struts of the annular outer wall directly toward a longitudinal axis that runs longitudinally through a center of the docking station, and to a corresponding one of a plurality of circumferentially spaced axially extending legs at least partially defining the annular valve seat. The outer wall is configured to conform to an interior shape of a blood vessel, when expanded inside the blood vessel, such that the outer wall can expand in multiple locations to conform to multiple bulges of the blood vessel and can contract in multiple locations to conform to multiple narrowed regions of the blood vessel.Type: ApplicationFiled: April 1, 2022Publication date: July 21, 2022Inventors: Liron Tayeb, Eran Goldberg, David Maimon, Adi Carmi, Arie Tylis, Ralph Schneider, Mohammad Jafari, Hengchu Cao, Eitan Atias
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Patent number: 11291540Abstract: Docking stations for transcatheter valves are described. The docking stations can include an expandable frame, at least one sealing portion, and a valve seat. The expandable frame can be configured to conform to an interior shape of a portion of the circulatory system when expanded inside the circulatory system. The sealing portion can be configured to contact an interior surface of the circulatory system to create a seal. The valve seat can be connected to the expandable frame and can be configured to support an expandable transcatheter valve. The docking stations are adaptable to different anatomies/locations to allow implantation of a transcatheter valve in a variety of anatomies/locations.Type: GrantFiled: July 13, 2018Date of Patent: April 5, 2022Assignee: Edwards Lifesciences CorporationInventors: Liron Tayeb, Eran Goldberg, David Maimon, Adi Carmi, Arie Tylis, Ofir Witzman, Ralph Schneider, Mohammad Jafari, Hengchu Cao, Eason Michael Abbott, Dustin P. Armer, Michael D. Franklin, Tomer Saar, Anatoly Dvorsky, John J. Desrosiers, Daniel James Murray, Michael G. Valdez, Assaf Bash, Amir Blumenfeld, Noa Axelrod, Eitan Atias
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Publication number: 20220008200Abstract: Certain embodiments of the present disclosure provide a prosthetic valve (e.g., prosthetic heart valve) and a valve delivery apparatus for delivery of the prosthetic valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic heart valve through the aorta (i.e., in a retrograde approach) for replacing a diseased native aortic valve. The delivery apparatus in particular embodiments is configured to deploy a prosthetic valve from a delivery sheath in a precise and controlled manner at the target location within the body.Type: ApplicationFiled: September 24, 2021Publication date: January 13, 2022Inventors: Michael J. Popp, David Alon, Jun Liu, Luca Pesce, Mohammad Jafari
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Patent number: 11129713Abstract: A prosthetic heart valve delivery system can include a catheter portion having a sheath that can cover and uncover the prosthetic heart valve mounted on an inner shaft, a handle having a sheath actuator operatively coupled to a proximal portion of the sheath, the inner shaft extending through the handle, and a shaft retractor releasably coupled to a proximal portion of the handle and fixedly coupled to a proximal portion of the inner shaft. A sheath actuator can move the sheath axially relative to the inner shaft when the shaft retractor is coupled to the handle, and a proximal movement of the sheath relative to the inner shaft can cause the sheath to uncover the prosthetic heart valve. The shaft retractor can be operable to retract the inner shaft and the nosecone proximally relative to the sheath when the shaft retractor is released from the handle.Type: GrantFiled: October 22, 2020Date of Patent: September 28, 2021Assignee: Edwards Lifesciences CorporationInventors: Michael J. Popp, David Alon, Jun Liu, Luca Pesce, Mohammad Jafari
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Publication number: 20210038385Abstract: A prosthetic heart valve delivery system can include a catheter portion having a sheath that can cover and uncover the prosthetic heart valve mounted on an inner shaft, a handle having a sheath actuator operatively coupled to a proximal portion of the sheath, the inner shaft extending through the handle, and a shaft retractor releasably coupled to a proximal portion of the handle and fixedly coupled to a proximal portion of the inner shaft. A sheath actuator can move the sheath axially relative to the inner shaft when the shaft retractor is coupled to the handle, and a proximal movement of the sheath relative to the inner shaft can cause the sheath to uncover the prosthetic heart valve. The shaft retractor can be operable to retract the inner shaft and the nosecone proximally relative to the sheath when the shaft retractor is released from the handle.Type: ApplicationFiled: October 22, 2020Publication date: February 11, 2021Applicant: Edwards Lifesciences CorporationInventors: Michael J. Popp, David Alon, Jun Liu, Luca Pesce, Mohammad Jafari
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Publication number: 20200170793Abstract: A handle for a prosthetic heart valve delivery apparatus includes a housing, a motorized mechanism, and a holding mechanism. The housing is configured to be hand-held by a user and includes a distal opening. The motorized mechanism is disposed within the housing and is configured to be releasably coupled to a proximal end portion of a first shaft of the prosthetic heart valve delivery apparatus. When actuated, the motorized mechanism is configured to rotate the first shaft relative to the housing. The holding mechanism is disposed inside the housing and is configured to engage a proximal end portion of a second shaft of the prosthetic heart valve delivery apparatus such that the second shaft is axially and rotationally fixed relative to the housing, and the first shaft extends through the second shaft.Type: ApplicationFiled: February 5, 2020Publication date: June 4, 2020Inventors: Michael J. Popp, David Alon, Jun Liu, Luca Pesce, Mohammad Jafari
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Patent number: 10470876Abstract: Embodiments of prosthetic valves for implantation within a native mitral valve are provided. A prosthetic valve may comprise a radially compressible main body and a one-way valve portion. The prosthetic valve may further comprise one or more ventricular anchors coupled to the main body and disposed outside of the main body. The ventricular anchors may be configured such that a reduced profile of the prosthetic valve is possible. A space may be provided between an outer surface of the main body and the ventricular anchors for receiving native mitral valve leaflets. The prosthetic valve may include an atrial sealing member adapted for placement above the annulus of the mitral valve. Methods and devices for receiving the native mitral valve leaflets between the ventricular anchors and the main body are described.Type: GrantFiled: November 8, 2016Date of Patent: November 12, 2019Assignee: Edwards Lifesciences CorporationInventors: Nikolay Gurovich, Mohammad Jafari, Liron Tayeb, Ilan Tamir, Ziv Yohanan, Noam Nir, David Maimon, Boaz Manash
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Publication number: 20190000615Abstract: Docking stations for transcatheter valves are described. The docking stations can include an expandable frame, at least one sealing portion, and a valve seat. The expandable frame can be configured to conform to an interior shape of a portion of the circulatory system when expanded inside the circulatory system. The sealing portion can be configured to contact an interior surface of the circulatory system to create a seal. The valve seat can be connected to the expandable frame and can be configured to support an expandable transcatheter valve. The docking stations are adaptable to different anatomies/locations to allow implantation of a transcatheter valve in a variety of anatomies/locations.Type: ApplicationFiled: July 13, 2018Publication date: January 3, 2019Inventors: Liron Tayeb, Eran Goldberg, David Maimon, Adi Carmi, Arie Tylis, Ofir Witzman, Ralph Schneider, Mohammad Jafari, Hengchu Cao, Eason Michael Abbott, Dustin P. Armer, Michael D. Franklin, Tomer Saar, Anatoly Dvorsky, John J. Desrosiers, Daniel James Murray, Michael G. Valdez, Assaf Bash, Amir Blumenfeld, Noa Axelrod, Eitan Atias
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Patent number: 9775591Abstract: Embodiments of the present disclosure are directed to implantable sealing devices, delivery apparatuses, and methods of their use, for closing surgical openings or defects in a sidewall of a vessel in a subject. In several embodiments, the disclosed implantable sealing devices, delivery apparatuses, and methods can be used to close a surgical opening in a sidewall of the heart.Type: GrantFiled: November 20, 2014Date of Patent: October 3, 2017Assignee: Edwards Lifesciences CorporationInventors: Sergio Delgado, Ralph Schneider, Stanton J. Rowe, Ming H. Wu, Mohammad Jafari, Jon Boomgarden
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Publication number: 20170128199Abstract: Embodiments of prosthetic valves for implantation within a native mitral valve are provided. A prosthetic valve may comprise a radially compressible main body and a one-way valve portion. The prosthetic valve may further comprise one or more ventricular anchors coupled to the main body and disposed outside of the main body. The ventricular anchors may be configured such that a reduced profile of the prosthetic valve is possible. A space may be provided between an outer surface of the main body and the ventricular anchors for receiving native mitral valve leaflets. The prosthetic valve may include an atrial sealing member adapted for placement above the annulus of the mitral valve. Methods and devices for receiving the native mitral valve leaflets between the ventricular anchors and the main body are described.Type: ApplicationFiled: November 8, 2016Publication date: May 11, 2017Inventors: Nikolay Gurovich, Mohammad Jafari, Liron Tayeb, Ilan Tamir, Ziv Yohanan, Noam Nir, David Maimon, Boaz Manash
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Patent number: 9498202Abstract: Disclosed herein are exemplary embodiments of suture securement devices that replace the need to tie knots in sutures. Some embodiments comprise an annular outer body and one or more suture engagement tabs extending inwardly from the outer body. The devices can comprise a superelastic and/or shape-memory material and have a generally in-plane initial configuration. The suture engagement portions are deformable out-of-plane to an active configuration with the outer body compressed and the tabs interlocked with each other. The device can be heat-set in the deformed configuration. The interlocked tabs exert a pinching force on sutures passing between them that restricts the sutures from sliding through the opening in one longitudinal direction.Type: GrantFiled: July 9, 2013Date of Patent: November 22, 2016Assignee: Edwards Lifesciences CorporationInventors: Mohammad Jafari, Ming H. Wu, Hengchu Cao, Ralph Schneider, Manouchehr A. Miraki
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Publication number: 20160166248Abstract: A multiple-fire securing device includes a hollow outer shaft, a reloader, a reloader movement assembly, a rail, and securing structures each defining an inner securing orifice. The reloader longitudinally moves within the outer shaft and has a distal end shaped to temporarily contact one of the securing structures. The rail is disposed within the reloader and has an installing location. The securing structures are disposed on the rail. The reloader movement assembly moves the reloader longitudinally in a distal direction to deliver a first securing structure to the installing location from a first proximal position and moves the reloader proximally away from the installing location without the first securing structure to a position in which the distal end of the reloader temporarily contacts a second one of the securing structures. The second and successive securing structures are moved one at a time to the installing location.Type: ApplicationFiled: December 10, 2015Publication date: June 16, 2016Inventors: Derek Dee Deville, Kevin W. Smith, Michael Walter Kirk, Carlos Rivera, George Nunez, Thomas O. Bales, JR., Korey Kline, Matthew A. Palmer, M. Sean McBrayer, Richard Cartledge, Max Pierre Mendez, Hengchu Cao, Anthony Peter Carcia, Kevin Dang, Carey Hendsbee, Brent K. Hoffman, Brian R. Jacobs, Mohammad Jafari, Brian Janish, Jeffrey L. Mahoney, Raffaele Mazzei, Manouchehr A. Miraki, Ryan Moehle, Jeremiah Morgan, Michael C. Murad, Travis Zenyo Oba, Ralph Schneider, Fabian Daniel Schroeder, Tyler Douglas Smith, Ming H. Wu
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Patent number: 9155619Abstract: Certain embodiments of the present disclosure provide a prosthetic valve (e.g., prosthetic heart valve) and a valve delivery apparatus for delivery of the prosthetic valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic heart valve through the aorta (i.e., in a retrograde approach) for replacing a diseased native aortic valve. The delivery apparatus in particular embodiments is configured to deploy a prosthetic valve from a delivery sheath in a precise and controlled manner at the target location within the body.Type: GrantFiled: February 24, 2012Date of Patent: October 13, 2015Assignee: Edwards Lifesciences CorporationInventors: Jun Liu, Luca Pesce, Michael Popp, David Alon, Mohammad Jafari, Sergio Delgado
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Publication number: 20150142049Abstract: Embodiments of the present disclosure are directed to implantable sealing devices, delivery apparatuses, and methods of their use, for closing surgical openings or defects in a sidewall of a vessel in a subject. In several embodiments, the disclosed implantable sealing devices, delivery apparatuses, and methods can be used to close a surgical opening in a sidewall of the heart.Type: ApplicationFiled: November 20, 2014Publication date: May 21, 2015Applicant: EDWARDS LIFESCIENCES CORPORATIONInventors: Sergio Delgado, Ralph Schneider, Stanton J. Rowe, Ming H. Wu, Mohammad Jafari, Jon Boomgarden
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Publication number: 20140031864Abstract: Disclosed herein are exemplary embodiments of suture securement devices that replace the need to tie knots in sutures. Some embodiments comprise an annular outer body and one or more suture engagement tabs extending inwardly from the outer body. The devices can comprise a superelastic and/or shape-memory material and have a generally in-plane initial configuration. The suture engagement portions are deformable out-of-plane to an active configuration with the outer body compressed and the tabs interlocked with each other. The device can be heat-set in the deformed configuration. The interlocked tabs exert a pinching force on sutures passing between them that restricts the sutures from sliding through the opening in one longitudinal direction.Type: ApplicationFiled: July 9, 2013Publication date: January 30, 2014Inventors: Mohammad Jafari, Ming H. Wu, Hengchu Cao, Ralph Schneider
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Publication number: 20120239142Abstract: Certain embodiments of the present disclosure provide a prosthetic valve (e.g., prosthetic heart valve) and a valve delivery apparatus for delivery of the prosthetic valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic heart valve through the aorta (i.e., in a retrograde approach) for replacing a diseased native aortic valve. The delivery apparatus in particular embodiments is configured to deploy a prosthetic valve from a delivery sheath in a precise and controlled manner at the target location within the body.Type: ApplicationFiled: February 24, 2012Publication date: September 20, 2012Inventors: Jun Liu, Luca Pesce, Michael Popp, David Alon, Mohammad Jafari, Sergio Delgado
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Patent number: RE47209Abstract: Disclosed herein are exemplary embodiments of suture securement devices that replace the need to tie knots in sutures. Some embodiments comprise an annular outer body and one or more suture engagement tabs extending inwardly from the outer body. The devices can comprise a superelastic and/or shape-memory material and have a generally in-plane initial configuration. The suture engagement portions are deformable out-of-plane to an active configuration with the outer body compressed and the tabs interlocked with each other. The device can be heat-set in the deformed configuration. The interlocked tabs exert a pinching force on sutures passing between them that restricts the sutures from sliding through the opening in one longitudinal direction.Type: GrantFiled: April 27, 2017Date of Patent: January 22, 2019Assignee: Edwards Lifesciences CorporationInventors: Mohammad Jafari, Ming H. Wu, Hengchu Cao, Ralph Schneider, Manouchehr A. Miraki