Patents by Inventor Mohammad KHAZAEI

Mohammad KHAZAEI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND USES FOR NDFIP1 FUSION POLYPEPTIDES IN TREATING NEURODEGENERATIVE DISEASES, BRAIN AND/OR TRAUMATIC AND NON-TRAUMATIC SPINAL CORD INJURIES, AND/OR OPTIC NEUROPATHIES
    Publication number: 20240391967
    Abstract: Disclosed herein are methods for treating a neurodegenerative disease and/or an optic nerve, brain and/or spinal cord injury using a Ndfip1 fusion polypeptide, a Ndfip1 nucleic acid molecule, a construct or expression cassette comprising the Ndfip1 nucleic acid molecule, and a cell comprising the construct and/or expression the fusion polypeptide.
    Type: Application
    Filed: December 2, 2021
    Publication date: November 28, 2024
    Applicant: University Health Network
    Inventors: Michael George FEHLINGS, Mohammad KHAZAEI
  • NEURAL PROGENITOR CELLS AND THERAPEUTIC USES OF SAME
    Publication number: 20240342218
    Abstract: The present disclosure relates generally to neural progenitor cells and therapeutic uses thereof. More particularly, the present disclosure provides cervical spinal cord-specific neural progenitor cells (cerNPCs), methods of producing cerNPCs, pharmaceutical compositions comprising cerNPCs. and methods of treating neurological diseases or disorders with the cerNPCs.
    Type: Application
    Filed: August 3, 2022
    Publication date: October 17, 2024
    Applicant: University Health Network
    Inventors: Michael George FEHLINGS, Mohammad KHAZAEI, Christopher S. AHUJA
  • METHODS FOR GENERATING NEURAL PROGENITOR CELLS WITH A SPINAL CORD IDENTITY
    Publication number: 20240009248
    Abstract: Provided herein are methods of producing spNPCs from iPSCs or NPCs, cell populations, compositions comprising cell populations, and uses of spNPCs made using the methods described. The method can comprise: a. obtaining unpatterned NPCs, the unpatterned NPCs expressing neuroectodermal markers including Pax6 and Sox1; b. priming the unpatterned NPCs of step a; and c. patterning the primed unpatterned NPCs to produce spNPCS.
    Type: Application
    Filed: September 8, 2021
    Publication date: January 11, 2024
    Applicant: University Health Network
    Inventors: Michael G FEHLINGS, Mohammad KHAZAEI, Christopher S AHUJA