Abstract: Methods, systems and computer-readable storage media relate to determining optimal treatment information. The methods may include determining a dose distribution for one or more target regions by applying a deformation parameter to a treatment plan dose distribution for a subset of a plurality of phases. The method may also include determining one or more dose parameters based on the dose distribution for the subset of the plurality of phases. The one or more dose parameters may represent a motion of the dose distribution over the plurality of phases for each region. The method may further include determining optimal treatment information based on the one or more dose parameters. The optimal treatment information may include optimal phase and associated dose distribution and the optimal phase may be a phase having a minimum total dose for the one or more target regions.

Abstract: Methods, systems and computer-readable storage media relate to determining individualized treatment planning margins. The methods may include processing motion data of a target obtained from at least one marker for one or more periods. Each period may include a plurality of time intervals. The processing may include processing the motion data to determine an isocenter for each time interval along at least one of the axes of motion. The axes can include the x axis, the y axis, and/or the z axis. The method may include determining motion prediction data for each of the at least one of the axes; and determining treatment planning margins for each of the at least one of the axes based on the motion prediction data. The individualized treatment margins can be smaller and more optimal because the treatment margins can incorporate patient specific patterns of motion of a target (e.g., an organ).

Abstract: Methods, systems and computer-readable storage media relate to determining optimal treatment information. The methods may include determining a dose distribution for one or more target regions by applying a deformation parameter to a treatment plan dose distribution for a subset of a plurality of phases. The method may also include determining one or more dose parameters based on the dose distribution for the subset of the plurality of phases. The one or more dose parameters may represent a motion of the dose distribution over the plurality of phases for each region. The method may further include determining optimal treatment information based on the one or more dose parameters. The optimal treatment information may include optimal phase and associated dose distribution and the optimal phase may be a phase having a minimum total dose for the one or more target regions.

Abstract: Methods, systems and computer-readable storage media relate to determining individualized treatment planning margins. The methods may include processing motion data of a target obtained from at least one marker for one or more periods. Each period may include a plurality of time intervals. The processing may include processing the motion data to determine an isocenter for each time interval along at least one of the axes of motion. The axes can include the x axis, the y axis, and/or the z axis. The method may include determining motion prediction data for each of the at least one of the axes; and determining treatment planning margins for each of the at least one of the axes based on the motion prediction data. The individualized treatment margins can be smaller and more optimal because the treatment margins can incorporate patient specific patterns of motion of a target (e.g., an organ).