Patents by Inventor Mohammad MASJEDIZADEH

Mohammad MASJEDIZADEH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions of peptide inhibitors of Interleukin-23 receptor
    Patent number: 11939361
    Abstract: The present invention relates to compositions of peptide inhibitors of the interleukin-23 receptor (IL-23R) or pharmaceutically acceptable salt or solvate forms thereof, corresponding pharmaceutical compositions, methods and/or uses for treatment of autoimmune inflammation and related diseases and disorders.
    Type: Grant
    Filed: November 19, 2021
    Date of Patent: March 26, 2024
    Assignees: Janssen Pharmaceutica NV, Protagonist Therapeutics, Inc.
    Inventors: Giustino Di Pretoro, Dajun Sun, Gopal Rajan, Geraldine Broeckx, Nathalie Mertens, Shu Li, Felix Lai, Mohammad Masjedizadeh, Anne M. Fourie, Beverly Knight, David Polidori, Santhosh Francis Neelamkavil, Nishit Modi, Ashok Bhandari, Xiaoli Cheng
  • COMPOSITIONS OF PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR
    Publication number: 20220177532
    Abstract: The present invention relates to compositions of peptide inhibitors of the interleukin-23 receptor (IL-23R) or pharmaceutically acceptable salt or solvate forms thereof, corresponding pharmaceutical compositions, methods and/or uses for treatment of autoimmune inflammation and related diseases and disorders.
    Type: Application
    Filed: November 19, 2021
    Publication date: June 9, 2022
    Inventors: Giustino Di Pretoro, Dajun SUN, Gopal RAJAN, Geraldine BROECKX, Nathalie MERTENS, Shu LI, Felix LAI, Mohammad MASJEDIZADEH
  • PROCESSES FOR PREPARING AN FGFR INHIBITOR
    Publication number: 20210147417
    Abstract: Disclosed herein are processes for preparing 8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one and FGFR inhibitor, as well as polymorphs and/or salt forms thereof.
    Type: Application
    Filed: January 22, 2021
    Publication date: May 20, 2021
    Inventors: Jiang ZHU, Mohammad MASJEDIZADEH
  • Processes for preparing an FGFR inhibitor
    Patent number: 10899760
    Abstract: Disclosed herein are processes for preparing 8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one and FGFR inhibitor, as well as polymorphs and/or salt forms thereof.
    Type: Grant
    Filed: January 17, 2020
    Date of Patent: January 26, 2021
    Assignee: PRINCIPIA BIOPHARMA, INC.
    Inventors: Jiang Zhu, Mohammad Masjedizadeh
  • PROCESSES FOR PREPARING AN FGFR INHIBITOR
    Publication number: 20200148680
    Abstract: Disclosed herein are processes for preparing 8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one and FGFR inhibitor, as well as polymorphs and/or salt forms thereof.
    Type: Application
    Filed: January 17, 2020
    Publication date: May 14, 2020
    Inventors: Jiang ZHU, Mohammad MASJEDIZADEH
  • Processes for preparing an FGFR inhibitor
    Patent number: 10538518
    Abstract: To an appropriate reactor equipped with mechanical stirrer was charged acetic acid (12 L), tert-butyl 4-(3-(6-(3,5-dimethoxyphenyl)-2-(methylthio)-7-oxopyrido[2,3-d]pyrimidin-8(7H)-yl)propyl)piperazine-1-carboxylate (2000 g) and triethylamine (639 g, 2.3 eq.). Internal temperature was adjusted to approximately 20° C. and N-chlorosuccinimide (1651 g, 4.5 eq.) was added at 20-30° C. Reaction was stirred for 2 hours. Ethyl acetate (30 L) was added. 5% aqueous NaCl solution (20 L) was added. The organic layer was separated and the aqueous layer was extracted with EtOAc. The combined organic layers were washed with 30% aqueous potassium carbonate solution (14 L). The organic layer was concentrated to ˜12 L and used for next step directly.
    Type: Grant
    Filed: August 10, 2016
    Date of Patent: January 21, 2020
    Assignee: Principia Biopharma, Inc.
    Inventors: Jiang Zhu, Mohammad Masjedizadeh
  • PROCESSES FOR PREPARING AN FGFR INHIBITOR
    Publication number: 20180215756
    Abstract: Disclosed herein are processes for preparing 8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one and FGFR inhibitor, as well as polymorphs and/or salt forms thereof.
    Type: Application
    Filed: August 10, 2016
    Publication date: August 2, 2018
    Applicant: Principia Biopharma, Inc.
    Inventors: Jiang ZHU, Mohammad MASJEDIZADEH