Patents by Inventor Mohammad S. Saedi

Mohammad S. Saedi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Forms of prostate specific antigens and methods for their detection
    Patent number: 7288636
    Abstract: Inactive precursor forms of PSA (pPSA) have been identified to exist in serum and tissues of patients with prostate cancer. Antibodies specific for pPSA are provided. Methods for detecting inactive precursors of PSA in human physiological fluid and tissues are also provided, as well as diagnostic kits and methods useful in the diagnosis and management of prostate cancer.
    Type: Grant
    Filed: February 23, 2001
    Date of Patent: October 30, 2007
    Assignee: Hybritech Incorporated
    Inventors: Stephen D. Mikolajczyk, Harry G. Rittenhouse, Abhay Kumar, Mohammad S. Saedi, Robert L. Wolfert
  • Complex of human kallikrein 2 (hK2) and protease inhibitor-6 (PI-6) in prostate tumor tissue and methods of using the complex and its constituents
    Patent number: 6472143
    Abstract: The present invention provides a novel complex of hK2 and PI-6 and methods of using the novel complex and its constituents. The novel complexes of hK2 and PI-6 of the present invention and the PI-6 exist at an elevated level in prostate cancer tissues. PI-6 also exists at an elevated level in other types of cancer cells. Therefore, the hK2-PI6 complexes and PI-6 of the present invention may be used as a serum marker for detecting cancers, particularly prostate cancer. They may also be used as an immunohistological marker to detect prostate cancer tissues. In accordance with the present invention, the hK2-PI6 complexes of the present invention may be detected in patient tissue samples by immunohistochemical and/or in patient fluid samples by in vitro immunoassay procedures. Diagnostic methods for detecting the existence of prostate cancer is also provided.
    Type: Grant
    Filed: September 22, 2000
    Date of Patent: October 29, 2002
    Assignee: Hyrbritech Incorporated
    Inventors: Stephen D. Mikolajczyk, Mohammad S. Saedi
  • Forms of prostate specific antigens and methods for their detection
    Publication number: 20020058291
    Abstract: Inactive precursor forms of PSA (pPSA) have been identified to exist in serum and tissues of patients with prostate cancer. Antibodies specific for pPSA are provided. Methods for detecting inactive precursors of PSA in human physiological fluid and tissues are also provided, as well as diagnostic kits and methods useful in the diagnosis and management of prostate cancer.
    Type: Application
    Filed: February 23, 2001
    Publication date: May 16, 2002
    Inventors: Stephen D. Mikolajczyk, Harry G. Rittenhouse, Abhay Kumar, Mohammad S. Saedi, Robert L. Wolfert
  • Novel complex of human kallikrein 2 (hK2) and protease inhibitor-6 (PI-6) in prostate tumor tissue and methods of using the complex
    Publication number: 20010031860
    Abstract: The present invention provides a novel complex of hK2 and PI-6 and methods of using the novel complex. The novel complexes of hK2 and PI-6 of the present invention exist at an elevated level in prostate cancer tissues. Therefore, the hK2-PI6 complexes of the present invention may be used as a serum marker for detecting prostate cancer. They may also be used as an immunohistological marker to detect prostate cancer tissues. In accordance with the present invention, the hK2-PI6 complexes of the present invention may be detected in patient tissue samples by immunohistochemical and/or in patient fluid samples by in vitro immunoassay procedures. Diagnostic kits and diagnostic methods for detecting the existence of prostate cancer are also provided.
    Type: Application
    Filed: June 15, 2001
    Publication date: October 18, 2001
    Applicant: Beckman Coulter, Inc. (formerly Beckman Instruments, Inc.)
    Inventors: Stephen D. Mikolajczyk, Mohammad S. Saedi
  • Complex of human kallikrein 2 (hK2) and protease inhibitor-6 (PI-6) in prostate tumor tissue and methods of using the complex
    Patent number: 6284873
    Abstract: The present invention provides a novel complex of hK2 and PI-6 and methods of using the novel complex. The novel complexes of hK2 and PI-6 of the present invention exist at an elevated level in prostate cancer tissues. Therefore, the hK2-PI6 complexes of the present invention may be used as a serum marker for detecting prostate cancer. They may also be used as an immunohistological marker to detect prostate cancer tissues. In accordance with the present invention, the hK2-PI6 complexes of the present invention may be detected in patient tissue samples by immunohistochemical and/or in patient fluid samples by in vitro immunoassay procedures. Diagnostic kits and diagnostic methods for detecting the existence of prostate cancer are also provided.
    Type: Grant
    Filed: March 12, 1999
    Date of Patent: September 4, 2001
    Assignee: Hybritech Incorporated
    Inventors: Stephen D. Mikolajczyk, Mohammad S. Saedi