Patents by Inventor Mohammad Shaheen Sharif

Mohammad Shaheen Sharif has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LIPID MEMBRANE STRUCTURE HAVING INTRANUCLEAR MIGRATING PROPERTY
    Publication number: 20150202154
    Abstract: A lipid membrane structure for delivering a substance into a nucleus of a cell, wherein lipid membrane is modified with (a) a polypeptide comprising the amino acid sequence of SEQ ID NO: 1, and/or (b) a polypeptide consisting of an amino acid sequence comprising the amino acid sequence of SEQ ID NO: 1, but including deletion and/or substitution and/or insertion of one or several amino acid residues, and having an activity of promoting migration of the lipid membrane structure into a nucleus of a cell, which can efficiently deliver a nucleic acid into a nucleus of an immunocyte such as dendritic cell.
    Type: Application
    Filed: February 9, 2015
    Publication date: July 23, 2015
    Applicant: NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
    Inventors: Hideyoshi HARASHIMA, Hidetaka AKITA, Mohammad Shaheen SHARIF, Takashi NAKAMURA, Soichiro ISHII, Shiroh FUTAKI
  • Lipid membrane structure having intranuclear migrating property
    Patent number: 8981044
    Abstract: A lipid membrane structure for delivering a substance into a nucleus of a cell, wherein lipid membrane is modified with (a) a polypeptide comprising the amino acid sequence of SEQ ID NO: 1, and/or (b) a polypeptide consisting of an amino acid sequence comprising the amino acid sequence of SEQ ID NO: 1, but including deletion and/or substitution and/or insertion of one or several amino acid residues, and having an activity of promoting migration of the lipid membrane structure into a nucleus of a cell, which can efficiently deliver a nucleic acid into a nucleus of an immunocyte such as dendritic cell.
    Type: Grant
    Filed: April 20, 2011
    Date of Patent: March 17, 2015
    Assignee: National University Corporation Hokkaido University
    Inventors: Hideyoshi Harashima, Hidetaka Akita, Mohammad Shaheen Sharif, Takashi Nakamura, Soichiro Ishii, Shiroh Futaki
  • LIPID MEMBRANE STRUCTURE HAVING INTRANUCLEAR MIGRATING PROPERTY
    Publication number: 20130122054
    Abstract: A lipid membrane structure for delivering a substance into a nucleus of a cell, wherein lipid membrane is modified with (a) a polypeptide comprising the amino acid sequence of SEQ ID NO: 1, and/or (b) a polypeptide consisting of an amino acid sequence comprising the amino acid sequence of SEQ ID NO: 1, but including deletion and/or substitution and/or insertion of one or several amino acid residues, and having an activity of promoting migration of the lipid membrane structure into a nucleus of a cell, which can efficiently deliver a nucleic acid into a nucleus of an immunocyte such as dendritic cell.
    Type: Application
    Filed: April 20, 2011
    Publication date: May 16, 2013
    Applicant: National University Corporation Hokkaido University
    Inventors: Hideyoshi Harashima, Hidetaka Akita, Mohammad Shaheen Sharif, Takashi Nakamura, Soichiro Ishii, Shiroh Futaki