Patents by Inventor Mohammed Ghanim Mehdi Alhilal

Mohammed Ghanim Mehdi Alhilal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of identifying microsatellite instability
    Patent number: 11519021
    Abstract: The present invention relates to methods and kits for identifying microsatellite instability (MSI) in a sample. In particular it relates to identifying microsatellite instability in a tumor sample, which may be from a subject suspected of having colorectal cancer or Lynch syndrome. The methods and kits can be used to identify mismatch repair defects. More particularly the invention relates to a panel of markers for a sequencing based MSI test, that can differentiate between MSI-H and MSS CRCs. The invention also allows for determination of biological significance, differentiating between PCR and sequencing errors and MSI induced indels/mutations.
    Type: Grant
    Filed: August 23, 2017
    Date of Patent: December 6, 2022
    Inventors: John Burn, Mohammed Ghanim Mehdi Alhilal, Francisco Mauro Santibanez-Koref, Lisa Redford, Michael Stewart Jackson
  • Methods of Identifying Microsatellite Instability
    Publication number: 20190194731
    Abstract: The present invention relates to methods and kits for identifying microsatellite instability (MSI) in a sample. In particular it relates to identifying microsatellite instability in a tumor sample, which may be from a subject suspected of having colorectal cancer or Lynch syndrome. The methods and kits can be used to identify mismatch repair defects. More particularly the invention relates to a panel of markers for a sequencing based MSI test, that can differentiate between MSI-H and MSS CRCs. The invention also allows for determination of biological significance, differentiating between PCR and sequencing errors and MSI induced indels/mutations.
    Type: Application
    Filed: August 23, 2017
    Publication date: June 27, 2019
    Applicant: Cancer Research Technology Limited
    Inventors: John Burn, Mohammed Ghanim Mehdi Alhilal, Franscisco Mauro Santibanez-Koref, Lisa Redford, Michael Stewart Jackson