Abstract: Provided are techniques that include determining a first set of operating parameters for a hydrocarbon well for a first period; determining, based on the first set of operating parameters, a skin factor (S1); determining, based on the skin factor (S1), a well model for the well; determining, a second set of operating parameters for the well for a second period; determining, based on the second set of operating parameters, well performance characteristics for the second period that include: a well pressure and a production flowrate for the second period of time; determining that the well performance characteristics for the second period are not consistent with the well model and, in response: determining, based on the second set of operating parameters, an updated skin factor; and determining, based on the updated skin factor (S2), an updated well model for the well.

Abstract: Systems, processes, and computer-readable media for determining lithology porosity of a formation rock from surface drilling parameters without the use of wireline logging. Lithology porosity at different depths in existing may be determined from the wireline logs. The lithology porosity may be shaly sand, tight sand, porous gas, or porous wet. A lithology porosity machine-learning model may be trained and calibrating using the data from a structured data set having surface drilling parameters from the existing wells and lithology porosity classifications from the wells. The lithology porosity machine learning model may then be used to determine a lithology porosity classification for a new well without the use of wireline logging.

Abstract: A water-based wellbore fluid may include an aqueous base fluid and a modified graphene shale inhibitor that comprises one or more substituents that are covalently bonded to graphene via a linking group. One of the one or more substituents may be a hydrocarbon group that has a number of carbon atoms in the range from 8 to 14.

Abstract: A computer system for single and consolidated real-time processing of event data relating to VAT tax refunds requests. The system communicates with multiple retailer systems and multiple user devices in connection with the processing of that event data in accordance with an adaptive processing rules schema. The system includes a distributed system interface that receives the event data from the plurality of distributed retailer networks in the form of event data transactions. The system is operated in accordance with a rules schema database that contains tax models applicable to various event data transactions. An event data processor receives the event data transactions and applies the tax models in the rules schema database and is then operable through a payment gateway processor to direct electronic transactions to occur in responding to the processing of the event data based at least in part on rules stored in the rules schema database in communication with the event data processor.

Abstract: According to one or more embodiments of the present disclosure, water-based drilling fluids may include an aqueous base fluid and one or more additives. In embodiments, water-based drilling fluids may include a lubricant blend including at least oleic acid and palmitoleic acid. The sum of the volume percent of the oleic acid and palmitoleic acid may be from 0.1 vol. % to 10 vol. % of the total volume of the water-based drilling fluid. In embodiments, water-based drilling fluids may include a lesser melting point fraction of jojoba oil in an amount of from 0.1 vol. % to 10 vol. % relative to the total volume of the water-based drilling fluid. At least 90% of the lesser melting point fraction of jojoba oil may have a melting point less than or equal to 15° C. Methods for drilling subterranean wells with the water-based drilling fluids are also disclosed.

Abstract: According to one or more embodiments of the present disclosure, water-based drilling fluids may include an aqueous base fluid and one or more additives. In embodiments, water-based drilling fluids may include a lubricant blend including at least oleic acid and palmitoleic acid. The sum of the volume percent of the oleic acid and palmitoleic acid may be from 0.1 vol. % to 10 vol. % of the total volume of the water-based drilling fluid. In embodiments, water-based drilling fluids may include a lesser melting point fraction of jojoba oil in an amount of from 0.1 vol. % to 10 vol. % relative to the total volume of the water-based drilling fluid. At least 90% of the lesser melting point fraction of jojoba oil may have a melting point less than or equal to 15° C. Methods for drilling subterranean wells with the water-based drilling fluids are also disclosed.

Abstract: The invention is directed to a method for diagnosing and treating a pulmonary lung disease by detecting a mutant S100A3 protein associated with pulmonary lung disease and by treating a subject with a functional S100A3 protein.

Abstract: Systems and methods for indirect monitoring of combustor dynamics in a gas turbine engine include collecting vibration data acquired by a vibration sensor, which is mounted proximate to an operational component positioned relative to a combustor of a gas turbine engine. The vibration data can be transformed into a frequency domain representation at periodic intervals. The relative signal strength of the vibration data can be determined over the one or more identified frequency bands. The relative signal strength can be adjusted with hysteresis at each of the one or more identified frequency bands. Occurrence of a combustor dynamics event at one or more specific resonant frequencies can be determined based at least in part on evaluation of the adjusted relative signal strength relative to one or more event detection threshold levels.

Abstract: The invention is directed to a method for diagnosing and treating fibrosis, especially pulmonary fibrosis, associated with mutation of the S100A13 and S100A3 genes. Methods for detecting and distinguishing the mutant forms of these genes are disclosed and ways to compensate for loss of function or aberrant function of the mutated S100A13 or S100A3 proteins are disclosed.

Abstract: The invention is directed to a method for diagnosing and treating a pulmonary lung disease by detecting a mutant S100A3 protein associated with pulmonary lung disease and by treating a subject with a functional S100A3 protein.

Abstract: In one embodiment, a cloud network provides cloud services to the one or more clients, where data usage of each client is monitored on a per client basis. If the data usage of any client is above a first predetermined threshold, then a WAN optimization platform is automatically implemented within the cloud network for the client having the data usage determined to be above the first predetermined threshold.

Abstract: Systems and methods for indirect monitoring of combustor dynamics in a gas turbine engine include collecting vibration data acquired by a vibration sensor, which is mounted proximate to an operational component positioned relative to a combustor of a gas turbine engine. The vibration data can be transformed into a frequency domain representation at periodic intervals. The relative signal strength of the vibration data can be determined over the one or more identified frequency bands. The relative signal strength can be adjusted with hysteresis at each of the one or more identified frequency bands. Occurrence of a combustor dynamics event at one or more specific resonant frequencies can be determined based at least in part on evaluation of the adjusted relative signal strength relative to one or more event detection threshold levels.

Abstract: There are only two ways to increase the amount of sample that can be purified by preparative reversed phase high performance liquid chromatography (Prep-RP-HPLC) in a single run: (1) The traditional approach is to use a bigger column (greater amount of stationary phase); and (2) Use displacement chromatography which uses the stationary phase more effectively. This invention describes a unique Prep-RP-HPLC technique that uses a C-18/C-8 derivatized silica coated with a hydrophobic quaternary ammonium salt or quaternary phosphonium salt to result in 7 to 12 fold increase in sample loading (of the crude mixture of organic compounds including synthetic crude peptides) in contrast to the conventional Prep-RP-HPLC technique. This increase in sample loading capacity and output is due to the additional surrogate stationary phase characteristic of the C-18/C8 bound quaternary salt. The quaternary surfactant is bound to the C-18/C-8 chains and silanols of the stationary phase.

Abstract: In an embodiment, a method comprises obtaining a second network address at a computer node, which has been already associated with a first network address and provided first keying information; sending, to a key server computer, an update message that comprises both the first network address and the second network address; using the first keying information to encrypt messages that the computer node sends from the second network address to one or more other members of a group.

Abstract: A multiple-sample-holder polishing setup for cross-section sample preparation and a method of making a device using the same are presented. The multiple-sample-holder polishing setup includes a frame. The frame has a hollow center, one or more long and short rods and a recess for accommodating a polishing head. The setup includes one or more sample holders. The sample holder is to be attached to the one or more long and short rods of the frame. A paddle is affixed to each sample holder. A sample is attached to the paddle. The sample is coated with a thin epoxy layer prior to polishing thereby allowing for easy inspection for site of interests as well as quick material removal.

Abstract: An example method includes receiving a request for a cloud capability set during an Internet Key Exchange negotiation associated with a virtual private network (VPN) tunnel between a subscriber and a cloud, wherein the cloud capability set comprises one or more cloud capabilities, mapping the request to one or more cryptographic modules that can support the cloud capability set, and offloading the VPN tunnel to the one or more cryptographic modules. The request can be an Internet Security Association and Key Management Protocol (ISAKMP) packet listing the one or more cloud capabilities in a private payload. The method may further include splitting the VPN tunnel between the cryptographic modules if no single cryptographic module can support substantially all the cloud capabilities in the cloud capability set. In some embodiments, the request is compared with a service catalog comprising authorized cloud capabilities.

Abstract: A sample is provided that can be purified by preparative reversed phase high performance liquid chromatography (Prep-RP-HPLC) in a single run in spite of recent advances in the production of reversed phase derivatized silica stationary supports: (1) The traditional approach is to use a bigger column (greater amount of stationary phase); and (2) Use displacement chromatography which (while labor intensive to develop) uses the stationary phase more effectively. This disclosure describes a unique Prep-RP-HPLC technique that uses a C-18/C-8 derivatized silica coated with a surfactant such as Triton X-100 to result in 7 to 10 fold increase in sample loading (of the crude mixture of organic compounds including synthetic crude peptides) in contrast to the conventional Prep-RP-HPLC technique. This increase in sample loading capacity and output is due to the additional surrogate stationary phase characteristic of the C-18/C8 adsorbed (bound) surfactant.

Abstract: Systems, methods, and other embodiments associated with any-to-any multicasting in a tunnel based virtual private network (VPN) are described. One example method includes calculating a resolved address for an unknown reverse path forwarding (RPF) neighbor in an any-to-any multicasting route. The resolved address is calculated using next hop resolution protocol (NHRP) resolution. The address is to be resolved based on control plane traffic. The NHRP address resolution is not to affect unicast routing. The example method may also include establishing the any-to-any multicasting route. Since the multicasting route is any-to-any (e.g., spoke-to-spoke), the multicasting route is not required to include a hub in the logical hub-and-spoke network.

Abstract: In an embodiment, a method comprises obtaining a second network address at a computer node, which has been already associated with a first network address and provided first keying information; sending, to a key server computer, an update message that comprises both the first network address and the second network address; using the first keying information to encrypt messages that the computer node sends from the second network address to one or more other members of a group.

Abstract: There are only two ways to increase the amount of sample that can be purified by preparative reversed phase high performance liquid chromatography (Prep-RP-HPLC) in a single run: (1) The traditional approach is to use a bigger column (greater amount of stationary phase); and (2) Use displacement chromatography which uses the stationary phase more effectively. This invention describes a unique Prep-RP-HPLC technique that uses a C-18/C-8 derivatized silica coated with a hydrophobic quaternary ammonium salt or quaternary phosphonium salt to result in 7 to 12 fold increase in sample loading (of the crude mixture of organic compounds including synthetic crude peptides) in contrast to the conventional Prep-RP-HPLC technique. This increase in sample loading capacity and output is due to the additional surrogate stationary phase characteristic of the C-18/C8 bound quaternary salt. The quaternary surfactant is bound to the C-18/C-8 chains and silanols of the stationary phase.