Patents by Inventor Mohammed Qadeeruddin

Mohammed Qadeeruddin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the Large Scale Production of Rizatriptan Benzoate
    Publication number: 20090062550
    Abstract: The present invention provides a method for preparing pure Rizatriptan benzoate having purity more than 99.5% and dimer impurity less than 0.1% comprises, i) Condensation of 1,2,4-Triazole with 4-Nitro benzyl bromide to yield 1-(4-nitrophenyl)methyl-1,2,4-triazole ii) Reducing the 1-(4-nitrophenyl)methyl-1,2,4-triazole to give 1-(4-aminophenyl)methyl-1,2,4-triazole iii) Converting 1-(4-aminophenyl)methyl-1,2,4-triazole to 1-(4-hydrazinophenyl)methyl-1,2,4-triazole hydrochloride iv) Condensing the hydrazine derivative with 4-(Dimethylamino) butanal diethylacetal to get Rizatriptan and v) Salification of Rizatriptan to Rizatriptan benzoate.
    Type: Application
    Filed: November 14, 2006
    Publication date: March 5, 2009
    Applicant: MATRIX LABORATORIES LTD
    Inventors: Purna Chandra Ray, Mohan Bandari, Mohammed Qadeeruddin, Seeta Ramanjaneyulu Gorantla