Patents by Inventor Mohammed Salauddin SHAIKH

Mohammed Salauddin SHAIKH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AN IMPROVED SUBSTRATE COCKTAIL ASSAY FOR HIGH-THROUGHPUT SCREENING OF CYTOCHROME P450 INHIBITORS
    Publication number: 20230272448
    Abstract: The present invention relates to obtaining single incubation condition for cocktail of probe substrates of 8 major Cytochrome P450 (CYP) isoforms to assess in vitro drug-drug interactions (DDIs) of novel drug candidates using liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) method. The present invention provides an improved and reduced substrate concentration and is developed in lower microsomal protein to avoid any non-specific binding of substrates with the microsomal proteins.
    Type: Application
    Filed: July 30, 2021
    Publication date: August 31, 2023
    Applicant: PIRAMAL PHARMA LIMITED
    Inventors: Vinod SANNA, Sharadsrikar KOTTURI, Mahendra SHUKLA, Mohammed Salauddin SHAIKH, Himani SAMAR