Patents by Inventor Mohan Chintalagiri Rao

Mohan Chintalagiri Rao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparaton of novel porphyrin derivatives and their use as PDT agents and fluorescence probes
    Patent number: 9040687
    Abstract: The present invention provides novel porphyrin derivatives represented by the general formula 1 and/or pharmaceutically acceptable derivatives thereof as NIR sensitizers for photodynamic therapeutic and diagnostic, biological and industrial applications. These porphyrin derivatives possess absorption (400-700 nm) and emission (600-750 nm) in the regions where biological chromophores do not absorb and hence are ideal candidates for application as NIR PDT agents and fluorescence sensors for medicinal applications in biology. The substituents like hydroxyl and glycolic units on these dyes render them amphiphilicity thereby improving their solubility in the aqueous media and cellular uptake and localization. These dyes show no toxicity in the dark and are highly selective towards tumor cells and stain nucleus very rapidly. Accordingly, these porphyrin derivatives are extremely useful as NIR PDT fluorescence sensors in photodynamic therapeutic and diagnostic, biological and industrial applications.
    Type: Grant
    Filed: January 21, 2011
    Date of Patent: May 26, 2015
    Assignee: COUNCIL OF SCIENTIFIC AND IDUSTRIAL RESEARCH
    Inventors: Danaboyina Ramaiah, Suneesh C. Karunakaran, Jisha S. Vadakkancheril, Chandrashekar K. Tavarekere, Srinivasan Alagar, Madhavan Radhakrishna Pillai, Sivakumari Asha Nair, Saneesh Babu P. Saras, Mohan Chintalagiri Rao, Kunchala Sridhar Rao
  • PROCESS FOR THE PREPARATON OF NOVEL PORPHYRIN DERIVATIVES AND THEIR USE AS PDT AGENTS AND FLUORESCENCE PROBES
    Publication number: 20120308485
    Abstract: The present invention provides novel porphyrin derivatives represented by the general formula 1 and/or pharmaceutically acceptable derivatives thereof as NIR sensitizers for photodynamic therapeutic and diagnostic, biological and industrial applications. These porphyrin derivatives posses absorption (400-700 nm) and emission (600-750 nm) in the regions where biological chromophores do not absorb and hence are ideal candidates for application as NIR PDT agents and fluorescence sensors for medicinal applications in biology. The substituents like hydroxyl and glycolic units on these dyes render them amphiphilicity thereby improving their solubility in the aqueous media and cellular uptake and localization. These dyes show no toxicity in the dark and are highly selective towards tumor cells and stain nucleus very rapidly. Accordingly, these porphyrin derivatives are extremely useful as NIR PDT fluorescence sensors in photodynamic therapeutic and diagnostic, biological and industrial applications.
    Type: Application
    Filed: January 21, 2011
    Publication date: December 6, 2012
    Applicant: Council of Scientific and Industrial Research
    Inventors: Danaboyina Ramaiah, Suneesh C. Karunakaran, Jisha S. Vadakkancheril, Chandrashekar K. Tavarekere, Srinivasan Alagar, Madhavan Radhakrishna Pillai, Sivakumari Asha Nair, Saneesh Babu P. Saras, Mohan Chintalagiri Rao, Kunchala Sridhar Rao