Patents by Inventor Mohan K. Sapru

Mohan K. Sapru has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • siRNA-mediated gene silencing of synuclein
    Patent number: 8389487
    Abstract: The present invention is directed to small interfering RNAs that down regulate expression of a synuclein gene and methods of using the small interfering RNAs.
    Type: Grant
    Filed: January 25, 2010
    Date of Patent: March 5, 2013
    Assignee: Ann & Robert Lurie Children's Hospital of Chicago
    Inventors: Martha C. Bohn, Mohan K. Sapru
  • siRNA-Mediated Gene Silencing of Synuclein
    Publication number: 20100286242
    Abstract: The present invention is directed to small interfering RNAs that down regulate expression of a synuclein gene and methods of using the small interfering RNAs.
    Type: Application
    Filed: January 25, 2010
    Publication date: November 11, 2010
    Inventors: Martha C. Bohn, Mohan K. Sapru
  • Neuregulin response element and uses therefor
    Patent number: 6162641
    Abstract: Methods for therapeutics and for screens are provided using a 15 bp sequence in the rat .epsilon.-subunit promoter that regulates PTPase, neuregulin and Ras-dependent gene expression. As this 15 bp sequence is necessary also for low .epsilon.-subunit gene expression in extrajunctional regions of the muscle fiber, the screens can identify agents that simultaneously and oppositely modulate expression in .epsilon.-subunit expression of synaptic and extrajunctional regions.
    Type: Grant
    Filed: June 5, 1998
    Date of Patent: December 19, 2000
    Assignee: The Regents of the University of Michigan
    Inventors: Daniel Goldman, Mohan K. Sapru