Abstract: Provided herein are antibodies, or antigen binding portions thereof, that bind to glucocorticoid-inducible TNF receptor (GITR). Also provided are uses of these proteins in therapeutic applications, such as in the treatment of cancer. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain variable region of the antibodies, and vectors comprising the polynucleotides encoding the heavy and/or light chain variable region of the antibodies.

Abstract: Provided herein are polynucleic acids and expression vectors for the expression and secretion of angiotensin peptide fragments (e.g., angiotensin-(1-7)) in probiotic bacteria. Provided herein are also probiotic compositions that enable efficient, cost-effective and patient friendly oral therapeutics for treating diverse pathological conditions that involve the renin-angiotensin system (RAS), e.g., pulmonary hypertension, diabetes, diabetic complications, cardiovascular diseases, and ocular inflammatory and neurodegenerative diseases.

Abstract: A microcode (uCode) hot-upgrade method for bare metal cloud deployment and associated apparatus. The uCode hot-upgrade method applies a uCode patch to a firmware storage device (e.g., BIOS SPI flash) through an out-of-band controller (e.g., baseboard management controller (BMC)). In conjunction with receiving a uCode patch, a uCode upgrade interrupt service is triggered to upgrade uCode for one or more CPUs in a bare-metal cloud platform during runtime of a tenant host operating system (OS) using an out-of-bound process. This innovation enables cloud service providers to deploy uCode hot-patches to bare metal servers for persistent storage and live-patch without touching the tenant operating system environment.

Abstract: The present disclosure relates to the technical field of Internet, in particular to a method for measuring network international outlet interfaces of a designated area. The method includes the following steps: acquiring a designated collection of routing interface paths and area location information of IP addresses of routing interface nodes; dividing the collected routing interface paths into critical hop complete paths and critical hop missing paths; determining whether a routing interface path is a critical hop complete path; using a 2-tuple to identify network international outlet interfaces of the routing interface path; and counting the quantity of the network international outlet interfaces of the measured area.

Abstract: Coated proppants include a proppant particle, a surface copolymer layer surrounding the proppant particle, and a resin layer surrounding the surface copolymer layer. The surface copolymer layer includes a copolymer of at least two monomers chosen from styrene, methyl methacrylate, ethylene, propylene, butylene, imides, urethanes, sulfones, carbonates, and acrylamides, where the copolymer is crosslinked by divinyl benzene. The resin layer includes a cured resin.

Abstract: A computer-implemented method for speech recognition, comprising receiving a frame of speech audio; encoding the frame of speech audio; calculating a halting probability based on the frame of speech audio; adding the halting probability to a first accumulator variable; in response to the first accumulator variable exceeding or reaching a first threshold, calculating a context vector based on the halting probability and the encoding of the frame of speech audio; performing a decoding step using the context vector to derive a token; and executing a function based on the derived token, wherein the executed function comprises at least one of text output or command performance.