Patents by Inventor Mohan Prasad

Mohan Prasad has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of aprepitant
    Patent number: 8080656
    Abstract: The present invention relates to a highly pure (2R,3S)-4-benzyl-3-(4-fluorophenyl)morpholin-2-yl 3,5-bis(trifluoromethyl)benzoate of Formula II, and a process for its preparation. The present invention further provides a process for preparation of Aprepitant of Formula I or pharmaceutically acceptable salt thereof, using the highly pure compound of Formula II. The present invention also provides a process for preparation of Aprepitant of Formula I or pharmaceutically acceptable salt thereof which comprises of cyclising the compound of Formula VII at elevated temperature, in the absence of solvent.
    Type: Grant
    Filed: October 5, 2006
    Date of Patent: December 20, 2011
    Assignee: Ranbaxy Laboratories Limited
    Inventors: Asok Nath, Hiten Sharadchandra Mehta, Mohan Prasad
  • PROCESS FOR THE PREPARATION OF ZIPRASIDONE
    Publication number: 20110207933
    Abstract: The invention relates to processes for the preparation of substantially pure ziprasidone. The invention also relates to the preparation of acid addition salts of ziprasidone. More particularly, it relates to the preparation of substantially pure hydrochloride salt of ziprasidone. The invention also relates to pharmaceutical compositions that include the substantially pure ziprasidone or ziprasidone hydrochloride and use of said compositions for treating schizophrenia.
    Type: Application
    Filed: May 4, 2011
    Publication date: August 25, 2011
    Applicant: RANBAXY LABORATORIES LIMITED
    Inventors: Yatendra KUMAR, Mohan PRASAD, Mahivir Singh KHANNA, Seema AHUJA
  • PROCESS FOR THE PREPARATION OF 3,4-EPOXY-2-AMINO-1-SUBSTITUTED BUTANE DERIVATIVES AND INTERMEDIATE COMPOUNDS THEREOF
    Publication number: 20110178305
    Abstract: The present invention relates to a process for the preparation of threo-3,4-epoxy-2-amino-1-substituted butane derivatives represented by general Formula I which comprises reacting compound of Formula III or salt thereof with an active ester of acid of Formula IV and treating the product thereof with base. The carbon atom bonded to the radical R3 in Formula I and IV is in the (R)-, (S)- or (R,S)-configuration. The compounds of Formula I and III, particularly in their (2S,3R) configuration are useful intermediates for the preparation of atazanavir bisulfate.
    Type: Application
    Filed: May 5, 2009
    Publication date: July 21, 2011
    Applicant: RANBAXY LABORATORIES LIMITED
    Inventors: Rakesh Singh, Prasad Yeragorla, Mahavir Singh Khanna, Mohan Prasad
  • PROCESS FOR PREPARING A CARBAPENEM ANTIBIOTIC COMPOSITION
    Publication number: 20110172201
    Abstract: The present invention relates to a process for preparing a carbapenem antibiotic composition. The present invention further relates to a carbapenem antibiotic composition substantially free of degradation impurities. The present invention further relates to a polymorphic form of ertapenem mono sodium designated as Form D and its preparation.
    Type: Application
    Filed: June 12, 2009
    Publication date: July 14, 2011
    Applicant: Ranbaxy Laboratories Limited
    Inventors: Vinod George, Bhupendra Vashishta, Mohan Prasad, Naresh Kumar, Vinod Kumar Arora
  • Process for the preparation of faropenem
    Patent number: 7977475
    Abstract: The present invention is related to processes for the preparation of faropenem, which comprises treating the compound of Formula II, with an alkali metal salt of a substituted or unsubstituted C5-10 carboxylic acid and a catalytic amount of a palladium complex in the presence of an organic solvent, followed by the treatment of the reaction mixture of with water and a water miscible solvent, and isolating a hydrate of an alkali metal salt of faropenem from the reaction mass, wherein water is not removed from the reaction mixture in water treatment or isolation steps.
    Type: Grant
    Filed: October 5, 2006
    Date of Patent: July 12, 2011
    Assignee: Ranbaxy Laboratories Limited
    Inventors: Neela Praveen Kumar, Mohan Prasad
  • Processes for the preparation of intermediates of valsartan
    Patent number: 7943794
    Abstract: The present invention relates to processes for the preparation of intermediates of valsartan.
    Type: Grant
    Filed: February 12, 2009
    Date of Patent: May 17, 2011
    Assignee: Ranbaxy Laboratories Limited
    Inventors: Ira Saxena, Asok Nath, Mohan Prasad
  • BARIUM SALT OF BENZIMIDAZOLE DERIVATIVE
    Publication number: 20110086884
    Abstract: The invention relates to crystalline barium salt of (S)-omeprazole, which is (S)-5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methyl]sulfinyl]-1H-benzimidazole. The invention also relates to processes for preparing crystalline barium salt of (S)-omeprazole and pharmaceutical compositions that include the crystalline barium salt of (S)-omeprazole so prepared.
    Type: Application
    Filed: December 20, 2010
    Publication date: April 14, 2011
    Inventors: Yatendra KUMAR, Mahavir Singh Khanna, Mohan Prasad
  • PROCESS FOR THE PREPARATION OF STERILE DORIPENEM
    Publication number: 20110082293
    Abstract: The present invention relates to a process for the preparation of sterile doripenem.
    Type: Application
    Filed: March 23, 2009
    Publication date: April 7, 2011
    Applicant: RANBAXY LABORATORIES LIMITED
    Inventors: Vinod George, Hashim Nizar Poovanathil Nagoor Meeran, Neera Tiwari, Mohan Prasad
  • Processes for the preparation of substituted sulfoxides
    Patent number: 7915422
    Abstract: The present invention relates to a process for enantioselective synthesis of substituted pyridinylmethyl sulfinyl-benzimidazole of compound of Formula (I). The process includes enantioselective catalytic oxidation of a substituted pyridinylmethyl prochiral sulfide derivative of compound of Formula (II) with an oxidizing agent in the presence of a chiral transition metal complex and a base in the absence of an organic solvent.
    Type: Grant
    Filed: October 4, 2005
    Date of Patent: March 29, 2011
    Assignee: Ranbaxy Laboratories Limited
    Inventors: Neela Praveen Kumar, Mahavir Singh Khanna, Mohan Prasad, Yatendra Kumar
  • Barium salt of benzimidazole derivative
    Patent number: 7872140
    Abstract: The invention relates to crystalline barium salt of (S)-omeprazole, which is (S)-5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methyl]sulfinyl]-1H-benzimidazole. The invention also relates to processes for preparing crystalline barium salt of (S)-omeprazole and pharmaceutical compositions that include the crystalline barium salt of (S)-omeprazole so prepared.
    Type: Grant
    Filed: May 15, 2009
    Date of Patent: January 18, 2011
    Assignee: Ranbaxy Laboratories Limited
    Inventors: Yatendra Kumar, Mahavir Singh Khanna, Mohan Prasad
  • PROCESS FOR THE PREPARATION OF SUBSTITUTED 1,3-OXATHIOLANES
    Publication number: 20100311970
    Abstract: The present invention relates to a process for the preparation of substituted 1,3-oxathiolanes. The present invention specifically relates to a process for the preparation of lamivudine.
    Type: Application
    Filed: April 30, 2008
    Publication date: December 9, 2010
    Applicant: RANBAXY LABORATORIES LIMITED
    Inventors: Neera Tewari, Dinesh Shashidharan Nair, Hashim Nizar Poovanathil Nagoor Meeran, Mohan Prasad
  • PROCESS FOR THE PREPARATION OF INTERMEDIATES OF TETRACYCLIC COMPOUNDS
    Publication number: 20100228030
    Abstract: The present invention relates to a process for the preparation of cis-intermediates of Formula II, (Formula II) wherein R1 represents hydrogen, (un)substituted alkyl, alkenyl, aryl, and X represents a leaving group, which are useful synthetic intermediates in the preparation of tetracyclic compounds having phosphodiesterase inhibitory activity.
    Type: Application
    Filed: June 28, 2008
    Publication date: September 9, 2010
    Applicant: RANBAXY LABORATORIES LIMITED
    Inventors: Dattatray B. Patil, Killol Patel, Ashok Prasad, Mohan Prasad
  • PROCESS FOR THE PREPARATION OF PANTOPRAZOLE SODIUM AND PANTOPRAZOLE SODIUM SESQUIHYDRATE
    Publication number: 20100210847
    Abstract: The present invention relates to a process for the preparation of pantoprazol sodium sesquihydrate of formula (I) and pantoprazole sodium.
    Type: Application
    Filed: July 17, 2008
    Publication date: August 19, 2010
    Applicant: RANBAXY LABORATORIES LIMITED
    Inventors: Ashish M. Trivedi, Shailendra Kumar Singh, Neera Tewari, Mohan Prasad
  • PROCESS FOR THE PREPARATION OF ORLISTAT
    Publication number: 20100179335
    Abstract: The present invention provides a process for preparing orlistat from amino orlistat using Pivaloyl Formic Anhydride (PFA) as an alkanoylating agent.
    Type: Application
    Filed: June 6, 2008
    Publication date: July 15, 2010
    Inventors: Patil Dattatray Bapuso, Killol Patel, Ashok Prasad, Keshav Deo, Mohan Prasad
  • BARIUM SALT OF BENZIMIDAZOLE DERIVATIVE
    Publication number: 20100145058
    Abstract: The invention relates to crystalline barium salt of (S)-omeprazole, which is (S)-5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methyl]sulfinyl]-1H-benzimidazole. The invention also relates to processes for preparing crystalline barium salt of (S)-omeprazole and pharmaceutical compositions that include the crystalline barium salt of (S)-omeprazole so prepared.
    Type: Application
    Filed: February 9, 2010
    Publication date: June 10, 2010
    Inventors: Yatendra KUMAR, Mahavir Singh Khanna, Mohan Prasad
  • NOVEL POLYMORPHIC FORMS OF MILNACIPRAN HYDROCHLORIDE
    Publication number: 20100145099
    Abstract: The present invention relates to polymorphic forms of milnacipran hydrochloride. The polymorphic forms are designated as Form (I), Form (II), Form (III), Form (IV) and Form V of milnacipran hydrochloride. The present invention also relates to processes for the preparation of the polymorphic forms.
    Type: Application
    Filed: February 28, 2008
    Publication date: June 10, 2010
    Applicant: RANBAXY LABORATORIES LIMITED
    Inventors: Roshan Ramesh Medhane, Nitin Maheswari, Keshav Deo, Mohan Prasad, Joydeep Kant
  • BARIUM SALT OF BENZIMIDAZOLE DERIVATIVE
    Publication number: 20100137607
    Abstract: The invention relates to crystalline barium salt of (S)-omeprazole, which is (S)-5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methyl]sulfinyl]-1H-benzimidazole. The invention also relates to processes for preparing crystalline barium salt of (S)-omeprazole and pharmaceutical compositions that include the crystalline barium salt of (S)-omeprazole so prepared.
    Type: Application
    Filed: February 9, 2010
    Publication date: June 3, 2010
    Inventors: Yatendra KUMAR, Mahavir Singh Khanna, Mohan Prasad
  • PROCESS FOR THE PREPARATION OF APREPITANT
    Publication number: 20100004242
    Abstract: The present invention relates to a highly pure (2R,3S)-4-benzyl-3-(4-fluorophenyl)morpholin-2-yl 3,5-bis(trifluoromethyl)benzoate of Formula II, and a process for its preparation. The present invention further provides a process for preparation of Aprepitant of Formula I or pharmaceutically acceptable salt thereof, using the highly pure compound of Formula II. The present invention also provides a process for preparation of Aprepitant of Formula I or pharmaceutically acceptable salt thereof which comprises of cyclising the compound of Formula VII at elevated temperature, in the absence of solvent.
    Type: Application
    Filed: October 5, 2006
    Publication date: January 7, 2010
    Inventors: Asok Nath, Hiten Sharadchandra Mehta, Mohan Prasad
  • CRYSTALLINE FORMS OF ATORVASTATIN MAGNESIUM
    Publication number: 20090306173
    Abstract: The present invention relates to crystalline forms of Atorvastatin magnesium and processes for their preparation. The crystalline forms of the present invention are designated as form X, form Y, form Z and form P of atorvastatin magnesium. The present invention further relates to pharmaceutical compositions comprising form X, form Y, form Z and form P of atorvastatin magnesium and method of using the crystalline forms.
    Type: Application
    Filed: June 2, 2009
    Publication date: December 10, 2009
    Inventors: Vipin TYAGI, Wajid Sajjad Jafri, Sanjay Kumar, Saridi Madhava Dileep Kumar, Swargam Sathyanarayana, Kaptan Singh, Mohan Prasad
  • BARIUM SALT OF BENZIMIDAZOLE DERIVATIVE
    Publication number: 20090259047
    Abstract: The invention relates to crystalline barium salt of (S)-omeprazole, which is (S)-5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methyl]sulfinyl]-1H-benzimidazole. The invention also relates to processes for preparing crystalline barium salt of (S)-omeprazole and pharmaceutical compositions that include the crystalline barium salt of (S)-omeprazole so prepared.
    Type: Application
    Filed: May 15, 2009
    Publication date: October 15, 2009
    Inventors: Yatendra KUMAR, Mahavir Singh Khanna, Mohan Prasad