Patents by Inventor Mohan S. Saini

Mohan S. Saini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5981206
    Abstract: A dry analytical element has been prepared for the assay of prostatic acid phosphatase at a pH of from about 3 to about 6.5. The element can be a single porous spreading zone or a multilayer structure. Within the element is a relatively nonhygroscopic aromatic phosphate substrate for the analyte which produces a phenol reaction product. This product is reacted with a diazonium or tetrazolium salt, also in the element, to produce a chromophore for detection. A buffer in the element maintains it at the proper pH during the assay.
    Type: Grant
    Filed: May 20, 1992
    Date of Patent: November 9, 1999
    Assignee: Johnson & Johnson Clinical Diagnostic Systems, Inc.
    Inventors: Thomas Charles Arter, Mohan S Saini
  • Patent number: 5578457
    Abstract: An immunoassay method and analytical elements for detecting carbamazepine drugs, for example, in body fluids, is described.
    Type: Grant
    Filed: August 7, 1992
    Date of Patent: November 26, 1996
    Assignee: Johnson & Johnson Clinical Diagnostics, Inc.
    Inventors: Barbara A. Brummond, Mohan S. Saini, Ignazio S. Ponticello
  • Patent number: 5543311
    Abstract: A labeled carbamazepine analogue is described comprising:(A) a label, of the type used in immunoassays, having an amine or sulfhydryl group such as horseradish peroxidase;(B) a carbamazepine nucleus; and(C) a linking chain linking the carboxamide group of the carbamazepine nucleus to the label, said linking chain having about 4 to about 40 atoms consisting of:(1) C.sub.2 to C.sub.6 alkylene groups; and(2) 5 to 7 membered heterocyclic ring groups, each group being joined into the linking group through chemical groups selected from(a) esters,(b) amides(c) heteroatoms selected from --O--, --S--, and --NR--; wherein R represents hydrogen or C.sub.1 to C.sub.6 alkyl; and(d) carbonyl.The new labeled analogues are useful in immunoassay elements and processes for detection of carbamazepine drugs, for example, in body fluids.
    Type: Grant
    Filed: August 7, 1992
    Date of Patent: August 6, 1996
    Assignee: Johnson & Johnson Clinical Diagnostics, Inc.
    Inventors: Barbara A. Brummond, Mohan S. Saini, Ignazio S. Ponticello
  • Patent number: 5395933
    Abstract: New carbamazepine hapten analogues are described comprising:(A) an active ester group;(B) a carbamazepine nucleus; and(C) a linking chain (i) linking the carboxamide group of the carbamazepine nucleus to the active ester group, said linking chain having about 4 to about 40 atoms consisting of:(1) alkylene groups; and(2) 5 to 7 membered heterocyclic ring groups, each group being joined into the linking group through chemical groups selected from(a) esters,(b) amides,(c) hetero atoms selected from --0--, --S--, and --NR--; wherein R represents hydrogen or C.sub.1 to C.sub.6 alkyl; and(d) carbonyl groups.The carbamazepine-active ester analogues are useful in preparing labeled carbamazepines. The labeled carbamazepines are useful in immunoassay elements and processes for the detection of carbamazepine drugs, for example, in body fluids.
    Type: Grant
    Filed: August 7, 1992
    Date of Patent: March 7, 1995
    Assignee: Eastman Kodak Company
    Inventors: Ignazio S. Ponticello, Mohan S. Saini