Abstract: The present application relates to an improved process for the formation of disulfide bonds in linaclotide. The present application also relates to an improved process for the purification of linaclotide.

Abstract: The present invention relates to a method and system to securely authenticate an operation request using a secure device. Automatic rejections are initiated on the basis of detection of mismatch of information by the secure device received from a server computer and an insecure terminal. The system and method further enables the user to manually confirm/reject operation requests by providing user inputs on an insecure terminal.

Abstract: An intelligent payment card and a method for performing a financial transaction using the payment card are disclosed. The payment card includes inter-alia a biometric sensor, an input module, and a display screen. The payment card is activated when a primary user successfully authenticates himself by the way of providing valid finger print(s) to the biometric sensor of the payment card. The payment card is removably embedded with criteria that dictate at least a maximum transaction amount, maximum number of transactions to be performed on the card and maximum threshold time for completing a transaction. The payment card also includes a processor unit which compares the authorization code input by the user with a unique identification number stored within the payment card, and upon successful authentication enables the user to perform desired financial transaction and also ensures that the removably embedded criteria are not violated during the financial transaction.

Abstract: The present invention relates to a method and system to securely authenticate an operation request using a secure device. Automatic rejections are initiated on the basis of detection of mismatch of information by the secure device received from a server computer and an insecure terminal. The system and method further enables the user to manually confirm/reject operation requests by providing user inputs on an insecure terminal.

Abstract: A novel biphasic pharmaceutial or nutraceutical composition delivers both an immediate and a sustained dose of a pharmaceutical or nutraceutical agent in the same unit dose. An oral unit dose of melatonin includes melatonin in a sustained-release matrix contained in a solid phase, such as a tablet of capsule, and also includes melatonin in a film dispersed on the surface of the solid phase. Approximately 80 to 90 weight percent of the total amount of melatonin of each unit is contained in the sustained-release matrix and the remainder in the film. The novel composition permits a mammal, including a human being, to both rapidly fall asleep and remain asleep for a desired period of time by releasing an immediate-release dose and a sustained-release dose of melatonin.

Abstract: Auto-configuration (i.e., without requiring manual intervention) of network services required to support operation of dependent network services. For example, when an administrator causes instantiation of (or installs) OSPF protocol, the firewall, QoS and NAT services are automatically configured. Due to such configuration, the deployment of additional services may be simplified.

Abstract: WISENG offers true convergence of multiple protocols and integrates the services offered by providers in the telecommunication industry. The system provides a seamless, efficient and real-time way to connect multiple telecommunication services on a unified platform, with an additional integration with service, billing and rating engines. Additionally, the system is fully customizable to offer real time integration of multiple service applications on one end and multiple protocols on the other end. The system is also capable of providing multiple protocol integration without the need to replace the overall infrastructure of the provider. The system, therefore, reduces the complex protocol conversion and service integration efforts, minimizes administrative costs related to inter-working/billing and reduces the capital costs related to upgrading and maintaining the core infrastructure of the provider.