Abstract: A method and system for spatiotemporal management of motion artifacts/blood pressure drifts in an arterial pressure waveform. The system includes an elastomeric sensor array in touch with a surface patch of skin over a superficial artery of a subject, an actuator mounted over the elastomeric sensor array, and a camera mounted on the actuator to capture image data that a controller processes. The controller measures the arterial pressure waveform having motion artifacts caused by elastomeric sensor array deformation on the skin over the artery in the pulsatile area and over the skin adjacent to the artery in the non-pulsatile area. Further, the controller determines spatiotemporal information of the motion artifact in the pulsatile and non-pulsatile areas, correcting the arterial pressure waveform by removing the motion artifact based on the spatiotemporal information to determine the physiological parameters.

Abstract: A method is directed to continuously, non-invasively, and directly measuring blood pressure, and includes providing a calibrated measurement device having a blood-flow control balloon and a sensor array. The method further includes placing the sensor array in a non-invasive manner over the surface of a patch of skin connected to an artery by adjoining soft tissues and inflating the blood-flow control balloon with a controlled amount of pressure. In response to the inflating of the blood-flow control balloon, changes in the artery geometry and forces are detected, via the sensor array, during a heartbeat cycle. The changes correspond to spatio-temporal signals from the artery or in the adjoining soft tissues. The spatio-temporal signals are measured and processed, via a controller, to determine blood-pressure parameters.

Abstract: A method is directed to continuously, non-invasively, and directly measuring blood pressure, and includes providing a calibrated measurement device having a blood-flow control balloon and a sensor array. The method further includes placing the sensor array in a non-invasive manner over the surface of a patch of skin connected to an artery by adjoining soft tissues and inflating the blood-flow control balloon with a controlled amount of pressure. In response to the inflating of the blood-flow control balloon, changes in the artery geometry and forces are detected, via the sensor array, during a heartbeat cycle. The changes correspond to spatio-temporal signals from the artery or in the adjoining soft tissues. The spatio-temporal signals are measured and processed, via a controller, to determine blood-pressure parameters.

Abstract: A method is directed to continuously, non-invasively, and directly measuring blood pressure, and includes providing a calibrated measurement device having a blood-flow control balloon and a sensor array. The method further includes placing the sensor array in a non-invasive manner over the surface of a patch of skin connected to an artery by adjoining soft tissues and inflating the blood-flow control balloon with a controlled amount of pressure. In response to the inflating of the blood-flow control balloon, changes in the artery geometry and forces are detected, via the sensor array, during a heartbeat cycle. The changes correspond to spatio-temporal signals from the artery or in the adjoining soft tissues. The spatio-temporal signals are measured and processed, via a controller, to determine blood-pressure parameters.

Abstract: An optomechanical sensor system is provided. The system can include a patient-worn surface displacement system comprising a deformable surface configured to be positioned against the patient adjacent to a superficial artery thereof, a plurality of optical markings disposed on the deformable surface, and an actuator configured to apply a pressure to hold the surface displacement system against the patient such that spatiotemporal movement of the superficial artery causes corresponding movement of the deformable surface and the plurality of optical markings. The system further includes an optical system which includes an imaging system, illumination, and with or without mirrors configured to visualize the plurality of optical markings at an oblique angle. The system determined the spatiotemporal movement of the superficial artery based on the received plurality of images and determine a cardiopulmonary parameter associated with the patient based thereon.

Abstract: A method is directed to continuously, non-invasively, and directly measuring blood pressure, and includes providing a calibrated measurement device having a blood-flow control balloon and a sensor array. The method further includes placing the sensor array in a non-invasive manner over the surface of a patch of skin connected to an artery by adjoining soft tissues and inflating the blood-flow control balloon with a controlled amount of pressure. In response to the inflating of the blood-flow control balloon, changes in the artery geometry and forces are detected, via the sensor array, during a heartbeat cycle. The changes correspond to spatio-temporal signals from the artery or in the adjoining soft tissues. The spatio-temporal signals are measured and processed, via a controller, to determine blood-pressure parameters.

Abstract: A ventricular ejection device adapted to be delivered percutaneously or surgically in to a ventricle of the heart, and the device comprising of an anchoring stent which is adapted to be fitted along a perimeter to a myocardium of the ventricle, and a recoiling part in physical coupling to the anchoring stent, extends from the perimeter of the anchoring stent to a center of the device, and adapted to extend or recoil based on flow of blood into and out of the ventricle.

Abstract: A ventricular ejection device adapted to be delivered percutaneously or surgically in to a ventricle of the heart, and the device comprising of an anchoring stent which is adapted to be fitted along a perimeter to a myocardium of the ventricle, and a recoiling part in physical coupling to the anchoring stent, extends from the perimeter of the anchoring stent to a center of the device, and adapted to extend or recoil based on flow of blood into and out of the ventricle.