Patents by Inventor Mohanraj Dhanabal

Mohanraj Dhanabal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230020092
    Abstract: Provided herein are compounds comprising cyclic cell penetrating peptides and antisense compounds. Also provided herein are methods of modulating splicing, inhibiting or regulating translation, mediating degradation, blocking expansions of nucleotide repeats, and treating disease using the aforementioned compounds.
    Type: Application
    Filed: December 21, 2020
    Publication date: January 19, 2023
    Inventors: Ziqing Qian, Xiang Li, Mahboubeh Kheirabadi, Mohanraj Dhanabal, Haoming Liu, Xiulong Shen, Kimberli Kamer, Natarajan Sethuraman
  • Publication number: 20060084054
    Abstract: The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: June 4, 2003
    Publication date: April 20, 2006
    Inventors: John Alsobrook, David Anderson, Jason Baumgartner, Constance Berghs, Ferenc Boldog, Catherine Burgess, Stacie Casman, Elina Catterton, Mohanraj Dhanabal, Shlomit Edinger, Karen Ellerman, Seth Ettenberg, Esha Gangolli, Valerie Gerlach, Linda Gorman, William Grosse, Erik Gunther, Xiaojia Guo, Vladimir Gusev, John Herrmann, Weizhen Ji, Ramesh Kekuda, Nikolai Khramtsov, William LaRochelle, Li Li, Hongping Liang, Kenneth Low, John MacDougall, Timothy Maclachlan, Uriel Malyankar, Kelly McQueeney, Amanda Mezick, Charles Miller, Isabelle Millet, Muralidhara Padigaru, Meera Patturajan, John Peyman, Xiaozhong Qian, Luca Rastelli, Daniel Rieger, Mark Rothenberg, Suresh Shenoy, Richard Shimkets, Glennda Smithson, Kimberly Spytek, David Stone, Sujatha Sukumaran, Edward Szekeres, Corine Vernet, Edward Voss, Adam Wolenc, Mei Zhong, Haihong Zhong
  • Publication number: 20040067882
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: November 5, 2002
    Publication date: April 8, 2004
    Inventors: John P. Alsobrook, Enrique Alvarez, David W. Anderson, Melanie Baron, Ferenc L. Boldog, Catherine E. Burgess, Stacie J. Casman, Andrei Chapoval, Mohanraj Dhanabal, Shlomit R. Edinger, Andrew Eisen, Karen Ellerman, Seth Ettenberg, Esha A. Gangolli, Valerie Gerlach, Linda Gorman, William M. Grosse, Xiaojia (Sasha) Guo, Craig Hackett, Weizhen Ji, Ramesh Kekuda, Nikolai V. Khramtsov, Denise M. Lepley, Li Li, John R. MacDougall, Uriel M. Malyankar, Ann Mazur, Kelly McQueeney, Peter S. Mezes, Charles E. Miller, Isabelle Millet, Vishnu Mishra, Muralidhara Padigaru, Meera Patturajan, Carol E. A. Pena, John A. Peyman, Luca Rastelli, Daniel K. Rieger, Mark E. Rothenberg, Suresh G. Shenoy, Richard A. Shimkets, Glennda Smithson, Steven K. Spaderna, Gary Starling, Kimberly A. Spytek, David J. Stone, Velizar T. Tchernev, Nancy Twomlow, Corine A.M. Vernet, Bryan D. Zerhusen, Edward Z. Voss, Mei Zhong
  • Publication number: 20040018977
    Abstract: The proteins of the invention are a family used to modulate the activity of cells and their ability to attract blood vessels. The proteins are used to inhibit angiogenesis, inhibit cell migration, and inhibit actin filament formation. These proteins are used in this context to diagnose and treat proliferative disorders such as cancer.
    Type: Application
    Filed: May 30, 2003
    Publication date: January 29, 2004
    Inventors: Enrique Alvarez, David W. Anderson, Mohanraj Dhanabal, Nikolai V. Khramtsov, William J. LaRochelle, Henri S. Lichenstein, Li Li, Chean Eng Ooi, Muralidhara Padigaru, Richard A. Shimkets, Mei Zhong
  • Publication number: 20030224991
    Abstract: Novel anti-angiogenesis proteins and the nucleic acid sequences which encode them are disclosed by the present invention.
    Type: Application
    Filed: March 11, 2003
    Publication date: December 4, 2003
    Inventors: Mohanraj Dhanabal, Frank Wu, William J. LaRochelle, Henri S. Lichenstein