Patents by Inventor Mohinder S. Kang

Mohinder S. Kang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • .alpha.-mannosidase inhibitors
    Patent number: 5262425
    Abstract: [4S-(4.alpha.,4a.beta.,5.beta.,6.alpha.,7.alpha.,7a.alpha.)]-Octahydro-1H-1 -pyrindine-4,5,6,7-tetrols and [4R-(4.alpha.,4a.alpha.,5.alpha.,6.beta.,7.beta.,7a.beta.)]-octahydro-1H-1 -pyrindine-4,5,6,7-tetrols are useful as inhibitors of alpha-mannosidase and are useful immunostimulants, chemoprotective and radioprotective agents and antimetastatic agents.
    Type: Grant
    Filed: June 3, 1992
    Date of Patent: November 16, 1993
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Robert A. Farr, Mohinder S. Kang, Norton P. Peet, Sai P. Sunkara
  • Derivatives of 6-aminooctahydroindolizinetriol
    Patent number: 5079254
    Abstract: Amide and ester derivatives of 6-amino-octahydro-1,7,8-indolizinetriol are described herein. The compounds are prepared from castanospermine by replacing the appropriate hydroxy function with an amino function while protecting the other hydroxy groups in the meantime. The compounds are useful as hexosaminidase inhibitors.
    Type: Grant
    Filed: June 4, 1990
    Date of Patent: January 7, 1992
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Paul S. Liu, Mohinder S. Kang
  • Hydroxymethyl-indolizidines and quinolizidines and their use as .alpha.-glucosidase I inhibitors
    Patent number: 5028614
    Abstract: The present invention describes a group of polyhydroxylated indolizidines and quinolizidines and their esters. These compounds are prepared starting from 2,6-dideoxy-2,6-dideoxy-2,6-imino-1,3,4,5-tetrakis-O- (phenylmethyl)-D-glycero-L-gulo-heptitol or a corresponding N-substituted compound. The compounds are useful in the treatment of diabetes and as .alpha.-glucosidase I inhibitors.
    Type: Grant
    Filed: March 30, 1990
    Date of Patent: July 2, 1991
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Paul S. Liu, Mohinder S. Kang, Roland S. Rogers, Barry L. Rhinehart