Patents by Inventor Mohini Jangi Desai

Mohini Jangi Desai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ALIGNMENT FREE FILTERING FOR IDENTIFYING FUSIONS
    Publication number: 20230002824
    Abstract: Cell free nucleic acids from a test sample obtained from an individual are analyzed to identify possible fusion events. Cell free nucleic acids are sequenced and processed to generate fragments. Fragments are decomposed into kmers and the kmers are either analyzed de novo or compared to targeted nucleic acid sequences that are known to be associated with fusion gene pairs of interest. Thus, kmers that may have originated from a fusion event can be identified. These kmers are consolidated to generate gene ranges from various genes that match sequences in the fragment. A candidate fusion event can be called given the spanning of one or more gene ranges across the fragment.
    Type: Application
    Filed: September 1, 2022
    Publication date: January 5, 2023
    Inventors: Xiao Yang, Hyunsung John Kim, Wenying Pan, Matthew H. Larson, Eric Michael Scott, Pranav Parmjit Singh, Mohini Jangi Desai
  • Alignment free filtering for identifying fusions
    Patent number: 11473137
    Abstract: Cell free nucleic acids from a test sample obtained from an individual are analyzed to identify possible fusion events. Cell free nucleic acids are sequenced and processed to generate fragments. Fragments are decomposed into kmers and the kmers are either analyzed de novo or compared to targeted nucleic acid sequences that are known to be associated with fusion gene pairs of interest. Thus, kmers that may have originated from a fusion event can be identified. These kmers are consolidated to generate gene ranges from various genes that match sequences in the fragment. A candidate fusion event can be called given the spanning of one or more gene ranges across the fragment.
    Type: Grant
    Filed: June 12, 2018
    Date of Patent: October 18, 2022
    Assignee: GRAIL, LLC
    Inventors: Xiao Yang, Hyunsung John Kim, Wenying Pan, Matthew H. Larson, Eric Michael Scott, Pranav Parmjit Singh, Mohini Jangi Desai
  • ALIGNMENT FREE FILTERING FOR IDENTIFYING FUSIONS
    Publication number: 20180355423
    Abstract: Cell free nucleic acids from a test sample obtained from an individual are analyzed to identify possible fusion events. Cell free nucleic acids are sequenced and processed to generate fragments. Fragments are decomposed into kmers and the kmers are either analyzed de novo or compared to targeted nucleic acid sequences that are known to be associated with fusion gene pairs of interest. Thus, kmers that may have originated from a fusion event can be identified. These kmers are consolidated to generate gene ranges from various genes that match sequences in the fragment. A candidate fusion event can be called given the spanning of one or more gene ranges across the fragment.
    Type: Application
    Filed: June 12, 2018
    Publication date: December 13, 2018
    Inventors: Xiao Yang, Hyungsung John Kim, Wenying Pan, Matthew H. Larson, Eric Michael Scott, Pranav Parmjit Singh, Mohini Jangi Desai