Patents by Inventor Mohit Kothare

Mohit Kothare has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESSES FOR THE PREPARATION OF (S)-2-(2,6-DIOXOPIPERIDIN-3-YL)-4-((2-FLUORO-4-((3-MORPHOLINOAZETIDIN-1-YL)METHYL)BENZYL)AMINO)ISOINDOLINE-1,3-DIONE
    Publication number: 20240228475
    Abstract: Provided herein are processes for the preparation of (S)-2-(2,6-dioxopipelidin-3-yl)-4-((2-fluoro-4-((3-morpholinoazetidin-1-yl) methyl) benzyl)amino)isoindoline-1, 3-dione, or a salt, solvate, hydrate, enantiomer, mixture of enantiomers, or isotopologue thereof, which is useful for treating, preventing, and managing various disorders. Also provided are solid forms of various intermediates and products obtained from the processes.
    Type: Application
    Filed: June 17, 2022
    Publication date: July 11, 2024
    Inventors: Ronald CARRASQUILLO-FLORES, Jian CHEN, Patrick CORONA, David DEL VALLE, Robert Francis DUNN, Megan EMMANUEL, Antonio C. FERRETTI, Richard Martin HEID, Amude KASSIM, Mohit KOTHARE, Wei LIU, Geoffrey Eugene PURDUM, Krishnakumar RANGANATHAN, Paula A. TAVARES-GRECO, Kelvin Hin-Yeong YONG, Yong YU, Chengmin ZHANG
  • MK2 inhibitors, synthesis thereof, and intermediates thereto
    Patent number: 11655257
    Abstract: The present invention provides methods of preparing a MK2 inhibitor, and intermediates related thereto.
    Type: Grant
    Filed: January 14, 2021
    Date of Patent: May 23, 2023
    Assignee: Celgene CAR LLC
    Inventors: Gregg Brian Feigelson, Maryll E. Geherty, Richard Martin Heid, Jr., Mohit Kothare, Hon-Wah Man, Alexander L. Ruchelman, John F. Traverse, Kelvin Hin-Yeong Yong, Chengmin Zhang
  • MK2 INHIBITORS, SYNTHESIS THEREOF, AND INTERMEDIATES THERETO
    Publication number: 20210139501
    Abstract: The present invention provides methods of preparing a MK2 inhibitor, and intermediates related thereto.
    Type: Application
    Filed: January 14, 2021
    Publication date: May 13, 2021
    Inventors: Gregg Brian Feigelson, Maryll E. Geherty, Richard Martin Heid, JR., Mohit Kothare, Hon-Wah Man, Alexander L. Ruchelman, John F. Traverse, Kelvin Hin-Yeong Yong, Chengmin Zhang
  • MK2 inhibitors, synthesis thereof, and intermediates thereto
    Patent number: 10894796
    Abstract: The present invention provides methods of preparing a MK2 inhibitor, and intermediates related thereto.
    Type: Grant
    Filed: March 15, 2018
    Date of Patent: January 19, 2021
    Assignee: Celgene CAR LLC
    Inventors: Gregg Brian Feigelson, Maryll E. Geherty, Richard Martin Heid, Jr., Mohit Kothare, Hon-Wah Man, Alexander L. Ruchelman, John F. Traverse, Kelvin Hin-Yeong Yong, Chengmin Zhang
  • MK2 INHIBITORS, SYNTHESIS THEREOF, AND INTERMEDIATES THERETO
    Publication number: 20200102326
    Abstract: The present invention provides methods of preparing a MK2 inhibitor, and intermediates related thereto.
    Type: Application
    Filed: March 15, 2018
    Publication date: April 2, 2020
    Inventors: Gregg Brian Feigelson, Maryll E. Geherty, Richard Martin Heid, JR., Mohit Kothare, Hon-Wah Man, Alexander L. Ruchelman, John F. Traverse, Kelvin Hin-Yeong Yong, Chengmin Zhang
  • Process for the preparation of substituted 2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
    Publication number: 20080064876
    Abstract: The present invention provides processes for the preparation of substituted 2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-diones which are useful, for example, for preventing or treating diseases or conditions related to an abnormally high level or activity of TNF-?. The invention can provide cost-effective and efficient processes for the commercial production of substituted 2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-diones, including, but not limited to, 4-[(N,N-dimethylhydrazono)methyl]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione, 4-aminomethyl-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione, and 4-[(acylamino)methyl]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-diones.
    Type: Application
    Filed: May 15, 2007
    Publication date: March 13, 2008
    Inventors: George Muller, Manohar Saindane, Chuansheng Ge, Mohit Kothare, Louise Cameron, Mark Rogers