Abstract: Correction of eye refractive errors such as presbyopia, hyperopia, myopia, and astigmatism by using either pre-tensioned or transcutaneously energized artificial muscle implants to change the axial length and the anterior curvatures of the eye globe by bringing the retina/macula region to coincide with the focal point. The implants are scleral constrictor bands, segments or ribs for inducing accommodation of a few diopters, to correct the refractive errors on demand or automatically. The implant comprises an active sphinctering band encircling the sclera, implanted under the conjunctiva and under the extraocular muscles to uniformly constrict the eye globe, to induce active temporary myopia (hyperopia) by increasing(decreasing) the length and curvature of the globe. Multiple and specially designed constrictor bands enable surgeons to correct astigmatism.

Abstract: Self-powered, bio- implantable, pressure adjustable mini-pump systems for medical applications including body fluid pressure control, drainage control, and drug delivery systems. The mini-pump systems include a primary mini-pump chamber having an anterior end attached to an implantable intake conduit. The device of the invention is further equipped with an adjustable variable flow valve or shunt in the form of a first cantilever slab, in combination with an anterior end one-way valve in the form of another cantilever slab. The posterior end of the mini-pump chamber is connected to a drainage conduit, via another one-way valve. Opposing diaphragm elements in the form of a pair of oscillatory flexing miniature ionic polymer metal composite IPPC artificial muscles, is used to vary the volume of the primary mini-pump chamber and thereby effect pumping action.

Abstract: Soft, multi-fingered resilient robotic fingers for selectively assisting heart ventricles or other organ to produce internal pressure and to pump blood, in synchrony with the systolic contraction of the ventricle or organ, as well as providing arrhythmia control of a beating heart. The apparatus is electrically-controlled and implantable. The plurality of soft fingers monitor and gently squeeze the heart (systole) or organ to enhance blood circulation and assist the heart or organ. The soft fingers work in harmony, by means of a micro-processor controlled solenoid or other linear robotic actuators such as metal-hydride actuators or polymeric artificial muscles, and a resilient body or a spring, to close once the solenoid is powered to retract away from the heart or organ when the solenoid is not powered. Monitoring electrodes can be affixed to the soft fingers. The power supply for the implanted device can be transcutaneously rechargeable batteries.

Abstract: Surgical correction of presbyopia and hyperopia by a circularly distributed assembly of mini-bridges implanted between the interior surfaces of the ciliary muscle and the exterior surface of the lens capsule, for augmenting the transmission of the contraction force of the ciliary muscle/zonule assembly to the lens capsule. The lens is symmetrically squeezed by mini-bridges acting in concert with the ciliary muscle thus changing the curvature of the lens. The mini-bridges are composite synthetic muscles comprising either passive biocompatible mini-bridges made with polymeric gels, silicone polymers or a composite, electromagnetically or mechanically deployable mini-bridges, inflatable balloons or synthetic muscles. The surgical procedure comprises using a ciliary muscle relaxant to stretch the lens/zonules/ciliary muscle assembly.

Abstract: Surgical correction of human eye refractive errors such as presbyopia, hyperopia, myopia, and stigmatism by using transcutaneously inductively energized artificial muscle implants to either actively change the axial length and the anterior curvatures of the eye globe. This brings the retina/macula region to coincide with the focal point. The implants use transcutaneously inductively energized scleral constrictor bands equipped with composite artificial muscle structures. The implants can induce enough accommodation of a few diopters, to correct presbyopia, hyperopia, and myopia on demand. In the preferred embodiment, the implant comprises an active sphinctering smart band to encircle the sclera, preferably implanted under the conjunctiva and under the extraocular muscles to uniformly constrict the eye globe, similar to a scleral buckle band for surgical correction of retinal detachment, to induce active temporary myopia (hyperopia) by increasing (decreasing) the active length of the globe.

Abstract: A new topical drug for enhancing hair growth or diminishing hair loss or alopecia, which comprises a mixture of a nitric oxide (NO) donor such as nitrovasodilators like minoxidil (RogaineRTM), nitroglycerin, L-arginine, isosorbide dinitrate, or nitroprusside, and a cyclic guanosine 3′,5′-monophosphate (cGMP) specific phosphodiesterase type 5 (PDE5) inhibitor such as sildenafil citrate (ViagraRTM) in a dermatologically acceptable solution mix. In this manner there will be increased vascular circulation and blood circulation to the hair bulbs and follicles and the effect of the combined compounds is enhanced synergistically.

Abstract: A new topical drug (ointment or eye drop) for treating glaucoma or ocular hypertension in a patient, which comprises a mixture of a nitric oxide (NO) donor such as nitrovasodilators like minoxidil, nitroglycerin, L-arginine, isosorbide dinitrate, or nitroprusside, and a cyclic guanosine 3′,5′-monophosphate (cGMP) specific phosphodiesterase type 5 (PDE5) inhibitor such as sildenafil citrate (ViagraRTM) in an ophthalmologically acceptable solution mix. In this manner there will be increased blood circulation to the optic nerve and the ocular hypotensive effect of the combined compounds is enhanced synergistically.

Abstract: Ion exchange membrane-based sensors, actuators and sensor/actuators and methods of making same for applications requiring sensing, actuating and controlling displacement. Sensors, actuators, and sensor/actuators are useful in biological as well as other applications. Encapsulation of the sensors, actuators, or sensor/actuators further increases the utility of the present invention. Devices according to the present invention made using lithium are preferred over those made using only sodium.

Abstract: Soft, multi-fingered resilient robotic fingers for selectively assisting the ventricles, and in particular the left ventricle, of a weak heart to produce internal pressure and to pump blood from one or more sides, in synchrony with the natural systolic contraction of the ventricle, as well as providing arrhythmia control of a beating heart. The apparatus is microprocessor and electrically-controlled and completely implantable. The plurality of soft fingers monitor and gently squeeze the heart (systole) to enhance blood circulation and assist a weak heart. The soft fingers work in harmony, by means of a micro-processor controlled solenoid or other linear robotic actuators such as metal-hydride actuators or polymeric artificial muscles, and a resilient body or a spring, to close once the solenoid is powered electrically and quickly retract away from the heart when the solenoid is not powered.

Abstract: A smart magnetometer which includes at least one cantilevered magnetostrictive/optical fiber structural bonded composite in a vibrationally isolated housing allowing an optical signal to be transmitted and detected from one optical fiber to another such that fluctuations of the surrounding magnetic field H will cause fluctuating mechanical torque on the composite magnetostrictive beam which will be applied to the bonded cantilevered optical fiber to deflect or misalign and cause modulation of the optical signal transmitted between the two fibers. This modulation can be calibrated to the dynamic variation of strength of a neighboring magnetic field to a precision and sensitivity of less than 1 fT and 1 fT/sqrtHz. The system is smart to selectively filter out any neighboring magnetic field with average strength smaller or greater than a certain critical value.

Abstract: New artificial muscles and actuators, that are operated by hydrogen gas as working fluid stored interstitially in metal hydrides as a hydrogen sponge. These artificial muscles and actuators are operated both electrically and thermally. The artificial muscles and actuators have fast response, are compact/light-weight, are noiseless, and produce high-power density. They can be used for biomedical, space, defense, micro-machines, and industrial applications.

Abstract: New polymeric materials and their fabrication methods that are electrically active in terms of sensing and actuation are invented. These materials are comprised of solid-state ion-conducting materials such as polyethylene oxide (PEO) and its derivatives or imbedded in a family of mixed polymer systems such as polydivinylbenzene (DVB) and polystyrene polymers. Such materials suitably electroded with conductive materials such as gold, platinum and silver exhibit large deformation (both two and three dimensionally) under low electric fields of 10's V/mm. Conversely, if these materials are deformed, they produce 10's of mV/mm electric fields that can be used as means of sensing or electromechanical powering devices for batteries.

Abstract: An apparatus and method of optical switching wherein a plurality of individual activation strips (18) are adhered longitudinally upon an optical channel, such as an optical fiber (14) to cause the fiber to undulate in 2½ dimensions when the activation strips are activated. The activation strips are activated with a constant or varying electrical source and are located at the free end of the optical fiber. Contraction and expansion of respective activation strips causes a free end of the optical fiber to be displaced or to undulate. A multichannel switch (100) operates by moving the free end of the selected input fiber and the free end of the selected output fiber toward one another so that the signal is sent from the input to the output fiber.

Abstract: Ion exchange membrane-based sensors, actuators and sensor/actuators and methods of making same for applications requiring sensing, actuating and controlling displacement. Sensors, actuators, and sensor/actuators are useful in biological as well as other applications. Encapsulation of the sensors, actuators, or sensor/actuators further increases the utility of the present invention. Devices according to the present invention made using lithium are preferred over those made using only sodium.

Abstract: New artificial muscles and actuators, that are operated by hydrogen gas as working fluid stored interstitially in metal hydrides as a hydrogen sponge. These artificial muscles and actuators are operated both electrically and thermally. The artificial muscles and actuators have fast response, are compact/light-weight, are noiseless, and produce high-power density. They can be used for biomedical, space, defense, micro-machines, and industrial applications.

Abstract: Implantable, pressure adjustable diaphragm pump systems which are scalable and are characterized by a common type of actuating mechanism. The pumps may be inductively and transcutaneously powered via adjacent, mutually inductive electromagnetic coils. Alternatively the pumps may be effectively “self” powered using a synthetic muscle attached to a local bending or twisting force. The pumps may be used in a range of applications from mechanical applications to medical applications such as intraocular pressure control for glaucoma patients, bodily fluid drainage control, and drug delivery systems. These pump systems each include a pumping chamber having an anterior end attached to an implantable influent conduit. In the case of an ocular pressure control device, the influent conduit is inserted into the anterior chamber of the eye.

Abstract: An apparatus and method of optical switching wherein a plurality of individual activation strips (18) are adhered longitudinally upon an optical channel, such as an optical fiber (14) to cause the fiber to undulate in 2½ dimensions when the activation strips are activated. The activation strips are activated with a constant or varying electrical source and are located at the free end of the optical fiber. Contraction and expansion of respective activation strips causes a free end of the optical fiber to be displaced or to undulate. A multichannel switch (100) operates by moving the free end of the selected input fiber and the free end of the selected output fiber toward one another so that the signal is sent from the input to the output fiber.

Abstract: An optical switch comprised of an artificial muscle activation material that is adhered longitudinally around an optical channel, such as an optical fiber or group of fibers, to cause the channel to undulate in 2-½ dimensions when the material is activated by a voltage source via electrodes on the surface of the artificial muscle activation material. The material can be applied to the optical channel in a series of longitudinal strips or as a jacket surrounding the channel. When activated by a voltage source, be it a constant source or a variable source varying in amplitude, frequency or polarity, the artificial muscle material bends, causing the optical channel to also bend. The artificial muscle activation material can be formed into an optical channel itself when formed into a channel and cladded to have internal reflection.

Abstract: An apparatus and method of optical switching wherein a plurality of activation strips (18) are adhered longitudinally around an optical channel, such as an optical fiber (14) to cause the fiber to undulate in 2½ dimensions when the activation strips are activated. The activation strips are activated with a voltage source. By varying the polarity of the activation strip itself or the source used to activate the activation strip, the optical fiber can be caused to undulate by contraction and expansion of respective activation strips.

Abstract: A chemical (coating and reduction)/mechanical/electrical treatment of ion-exchange materials (preferably ion-exchange membranes) to convert them to artificial muscles. The figure is a perspective view of an actuator of the invention showing the treated membrane actuator (A) with electrodes (25 and 26) placed at one end of the membrane, the electrodes being further attached to a power source (35). Artificial muscles created by the inventive method are capable of undergoing electrically-controllable large deformations resembling the behavior of biological muscles. A typical flap muscle of 0.2-0.4 mm thickness, 2-5 mm width and 20 mm length manufactured by the inventive process can achieve a completely reversible maximum deflection of 12-15 mm under a maximum voltage of 2.0-2.5 volts.