Patents by Inventor Mohyee E. Eldefrawi

Mohyee E. Eldefrawi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detection of botulinum toxin
    Patent number: 5932449
    Abstract: Recombinant antibody fragments (rFabs) specific to botulinum types A and B oxin complexes are provided. These rFabs are useful as immunosensors for detecting botulinum toxin in food, health care, and military applications. The DNA sequences coding for the rFabs are also disclosed.
    Type: Grant
    Filed: January 30, 1997
    Date of Patent: August 3, 1999
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Peter A. Emanuel, James J. Valdes, Mohyee E. Eldefrawi, James P. Burans
  • Butyryl-tyrosinyl spermine, analogs thereof and methods of preparing and using same
    Patent number: 5770625
    Abstract: The present invention provides a compound having the structure: ##STR1## wherein R.sub.1 is hydrogen or a branched or unbranched, substituted or unsubstituted aminoalkyl having from two to twenty atoms in the chain, R.sub.2 is hydrogen, methyl, or a branched or unbranched, substituted or unsubstituted alkyl having from two to twenty atoms in the chain; when R.sub.2 is methyl, R.sub.3 is either hydrogen or a substituted or unsubstituted aryl; and R.sub.4 is methyl, a branched or unbranched, substituted or unsubstituted alkyl, alkenyl, alkynyl, alkenynyl, or cycloalkyl having from two to twenty atoms in the chain, or a substituted or unsubstituted aryl group.The invention also concerns a method of preparing the compound from the venom, venom sacs or venom glands of the wasp Philanthus triangulun F. Additionally, the invention provides a method of chemically synthesizing the compound.
    Type: Grant
    Filed: July 14, 1994
    Date of Patent: June 23, 1998
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Koji Nakanishi, Amira T. Eldefrawi, Mohyee E. Eldefrawi, Peter N. R. Usherwood