Patents by Inventor Moin Ahson Saleem-Uddin

Moin Ahson Saleem-Uddin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • VECTOR
    Publication number: 20230175016
    Abstract: The present invention provides a viral vector comprising a nucleotide sequence encoding a complement protein, wherein the nucleotide sequence is operably linked to a podocyte-specific promoter and/or the viral vector is capable of specifically transducing podocytes.
    Type: Application
    Filed: June 30, 2021
    Publication date: June 8, 2023
    Inventors: Alan William Griffith, Lukas Stanczuk, Valeryia Kuzmuk, Chris Hollowood, Dominic Schmidt, Moin Ahson Saleem-Uddin, Gavin Iain Welsh
  • GENE THERAPY
    Publication number: 20230101788
    Abstract: The present invention provides an adeno-associated virus (AAV) vector gene therapy comprising a vascular endothelial growth factor (VEGF)C transgene; and minimal nephrin promoter NPHS1 or podocin promoter NPHS2. The gene therapy vector can be used to target podocytes within the glomerulus of the kidney in order to treat or prevent kidney disease, such as diabetic kidney disease.
    Type: Application
    Filed: March 4, 2021
    Publication date: March 30, 2023
    Applicant: THE UNIVERSITY OF BRISTOL
    Inventors: Rebecca R. Foster, Moin Ahson Saleem-Uddin, Gavin Iain Welsh
  • INHIBITOR OF BINDING BETWEEN PODOCIN AND KERATIN 8 FOR USE IN THE TREATMENT OF NEPHROTIC SYNDROME
    Publication number: 20220370482
    Abstract: A compound for use in the treatment of nephrotic syndrome in a subject in need thereof, wherein the compound is an inhibitor of binding between a target protein and keratin 8.
    Type: Application
    Filed: November 5, 2020
    Publication date: November 24, 2022
    Applicant: THE UNIVERSITY OF BRISTOL
    Inventors: Moin Ahson SALEEM-UDDIN, Gavin Ian WELSH
  • AAV GENE THERAPY FOR TREATING NEPHROTIC SYNDROME
    Publication number: 20220125950
    Abstract: The present invention provides an adeno-associated virus (AAV) vector gene therapy for use in treating a monogenic form of nephrotic syndrome, wherein the AAV vector comprises a NS-associated transgene and minimal nephrin promoter NPHS1 or podocin promoter NPHS2.
    Type: Application
    Filed: January 17, 2020
    Publication date: April 28, 2022
    Inventors: Moin Ahson Saleem-Uddin, Gavin lain Welsh
  • THERAPY
    Publication number: 20210402008
    Abstract: The application provides gene therapies for treating monogenic forms of nephrotic syndrome.
    Type: Application
    Filed: June 15, 2021
    Publication date: December 30, 2021
    Inventors: Moin Ahson Saleem-Uddin, Gavin Iain Welsh, Wen Yi Ding