Patents by Inventor Mojmir SUCHY

Mojmir SUCHY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOUNDS FOR DETECTION AND BINDING OF ALDEHYDES
    Publication number: 20230358732
    Abstract: Methods and kits for detecting a freely diffusing small molecule aldehyde in a subject or in a sample from a subject are described herein, comprising administering an aldehyde-binding compound of Formula I to the subject, or combining such a compound with the sample; and detecting the product of the compound of Formula I and the aldehyde. Detection of the product may involve imaging, such as MRI, CEST-MRI or positron emission tomography (PET) imaging; or may involve fluorescence or an electrochemical detection method. Relevant aldehydes detected according to the described method can be used to determine the presence or severity of a concussion in a subject.
    Type: Application
    Filed: June 29, 2023
    Publication date: November 9, 2023
    Inventors: Adam SHUHENDLER, Mojmir SUCHY, Trina DANG, Alexia KIRBY, Dominic GRAF
  • Methods and compounds for detection and binding of aldehydes
    Patent number: 11696960
    Abstract: Methods of detecting an aldehyde-containing compound in a subject or in a sample from a subject are described herein, comprising administering an aldehyde-binding compound of Formula I to the subject, or combining such a compound with the sample; and detecting the product of the compound of Formula I and the aldehyde-containing compound. Detection of the product may involve imaging, such as MRI, CEST-MRI or positron emission tomography (PET) imaging; or may involve fluorescence or an electrochemical detection method. Biologically relevant aldehydes detected according to the described method can be used to monitor conditions such as brain injury, neurodegenerative disorders such as Alzheimer's disease, diabetes, heart disease, and cancer.
    Type: Grant
    Filed: February 5, 2018
    Date of Patent: July 11, 2023
    Assignee: UNIVERSITY OF OTTAWA
    Inventors: Adam Shuhendler, Mojmir Suchy, Trina Dang
  • METHODS AND COMPOUNDS FOR DETECTION AND BINDING OF ALDEHYDES
    Publication number: 20200376144
    Abstract: Methods of detecting an aldehyde-containing compound in a subject or in a sample from a subject are described herein, comprising administering an aldehyde-binding compound of Formula I to the subject, or combining such a compound with the sample; and detecting the product of the compound of Formula I and the aldehyde-containing compound. Detection of the product may involve imaging, such as MRI, CEST-MRI or positron emission tomography (PET) imaging; or may involve fluorescence or an electrochemical detection method. Biologically relevant aldehydes detected according to the described method can be used to monitor conditions such as brain injury, neurodegenerative disorders such as Alzheimer's disease, diabetes, heart disease, and cancer.
    Type: Application
    Filed: February 5, 2018
    Publication date: December 3, 2020
    Inventors: Adam SHUHENDLER, Mojmir SUCHY, Trina DANG