Patents by Inventor Mokenge Malafa

Mokenge Malafa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THERANOSTIC TOOLS FOR MANAGEMENT OF PANCREATIC CANCER AND ITS PRECURSORS
    Publication number: 20200063215
    Abstract: The present invention concerns materials and methods for identifying and classifying pancreatic ductal adenocarcinoma (PDAC) precursors or intraductal papillary mucinous neoplasm (IPMN) using messenger RNAs, microRNAs, long non-coding RNAs, radiomic features, radiologic measures of abdominal/visceral obesity, and combinations thereof, as diagnostic markers for integration with clinical management and interventions for personalized care.
    Type: Application
    Filed: May 3, 2018
    Publication date: February 27, 2020
    Inventors: JENNIFER PERMUTH, DANIEL JEONG, JUNG CHOI, YOGANAND BALAGURUNATHAN, DUNG-TSA CHEN, MOKENGE MALAFA
  • Delta-Tocotrienol Treatment and Prevention of Pancreatic Cancer
    Publication number: 20080004233
    Abstract: Methods are disclosed for treating neoplastic disorders, such as pancreatic cancer, using tocotrienols; namely, gamma-tocotrienol and delta tocotrienol. The antitumorogenic effects of these compounds are shown both in vitro and in vivo using several human pancreatic cancer cell lines and MIA-PACA2 human pancreatic cancer cells xenografted in nude mice. Also disclosed are methods of testing the efficacy of potential chemotherapeutic agents by measuring their effect on surrogate endpoint biomarkers, such as Ki-67 and p27. Associated compounds are also disclosed.
    Type: Application
    Filed: June 26, 2007
    Publication date: January 3, 2008
    Applicant: UNIVERSITY OF SOUTH FLORIDA
    Inventors: Mokenge Malafa, Said Sebti