Patents by Inventor Momoko OTAKI

Momoko OTAKI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant fibrinogen high-production line and method for producing same
    Patent number: 10208101
    Abstract: The present invention provides a recombinant strain highly producing fibrinogen which is an animal cell strain coexpressing a fibrinogen and an ?2PI and/or PAI-2, genes encoding A? chain, B? chain and ? chain of fibrinogen, a production method of a recombinant strain highly producing fibrinogen, including introducing gene(s) encoding ?2PI and/or PAI-2 into an animal cell, and coexpressing fibrinogen and ?2PI and/or PAI-2 in the animal cell, and a production method of a recombinant fibrinogen including culturing a recombinant strain highly producing fibrinogen in a medium, and recovering fibrinogen from the obtained culture.
    Type: Grant
    Filed: December 26, 2014
    Date of Patent: February 19, 2019
    Assignee: JAPAN BLOOD PRODUCTS ORGANIZATION
    Inventors: Shusei Uno, Momoko Otaki, Kouji Murakami, Shoji Ideno
  • RECOMBINANT FIBRINOGEN HIGH-PRODUCTION LINE AND METHOD FOR PRODUCING SAME
    Publication number: 20160318990
    Abstract: The present invention provides a recombinant strain highly producing fibrinogen which is an animal cell strain coexpressing a fibrinogen and an ?2PI and/or PAI-2, genes encoding A? chain, B? chain and ? chain of fibrinogen, a production method of a recombinant strain highly producing fibrinogen, including introducing gene(s) encoding ?2PI and/or PAI-2 into an animal cell, and coexpressing fibrinogen and ?2PI and/or PAI-2 in the animal cell, and a production method of a recombinant fibrinogen including culturing a recombinant strain highly producing fibrinogen in a medium, and recovering fibrinogen from the obtained culture.
    Type: Application
    Filed: December 26, 2014
    Publication date: November 3, 2016
    Applicant: JAPAN BLOOD PRODUCTS ORGANIZATION
    Inventors: Shusei UNO, Momoko OTAKI, Kouji MURAKAMI, Shoji IDENO