Patents by Inventor Monah ABED

Monah ABED has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT OF ER+ BREAST CANCER COMPRISING HOMOLOGOUS RECOMBINATION DEFICIENCY USING PARG INHIBITOR
    Publication number: 20260216174
    Abstract: The present disclosure concerns new methods of treating cancer, e.g., breast cancer, in a patient in need thereof, comprising, inter alia, the use of poly(ADP-ribose) glycohydrolase (PARG) modulators, or pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: January 5, 2024
    Publication date: July 30, 2026
    Inventors: Monah ABED, Diana Marcela MUNOZ DELGADO, Mark LACKNER, Zineb MOUNIR, Vidya SESHADRI
  • HOMOLOGOUS RECOMBINATION REPAIR DEFICIENCY (HRD) AS A PREDICTIVE BIOMARKER FOR TREATING CANCER WITH WEE1 INHIBITORS
    Publication number: 20260083742
    Abstract: The present disclosure provides, among other things, methods for treating cancer comprising administering an effective dose of azenosertib, or a pharmaceutically acceptable salt thereof, to subjects selected to have a homologous recombination repair deficiency (HRD).
    Type: Application
    Filed: December 1, 2025
    Publication date: March 26, 2026
    Inventors: Jianhui Ma, Olivier Harismendy, Jiali Li, Ahmed Abdi Samatar, Samuel DePrimo, Catherine Lee, Monah Abed
  • PIPERAZINE SUBSTITUTED INDAZOLE COMPOUNDS AS INHIBITORS OF PARG
    Publication number: 20250376467
    Abstract: Provided herein are compounds of Formula (I): or a pharmaceutically acceptable salt thereof. The provided compounds are useful Poly ADP-ribose glycohydrolase (PARG) inhibitors. Additional utilities and advantages are described herein.
    Type: Application
    Filed: February 28, 2025
    Publication date: December 11, 2025
    Inventors: Paul A. BARSANTI, Michael Patrick DILLON, Firoz Ali JAIPURI, Ying-Zi XU, Xin LINGHU, Monah ABED
  • PIPERAZINE SUBSTITUTED INDAZOLE COMPOUNDS AS INHIBITORS OF PARG
    Publication number: 20230303556
    Abstract: Provided herein are compounds of Formula (I): or a pharmaceutically acceptable salt thereof. The provided compounds are useful Poly ADP-ribose glycohydrolase (PARG) inhibitors. Additional utilities and advantages are described herein.
    Type: Application
    Filed: March 22, 2023
    Publication date: September 28, 2023
    Inventors: Paul A. BARSANTI, Michael Patrick DILLON, Firoz Ali JAIPURI, Ying-Zi XU, Xin LINGHU, Monah ABED