Abstract: The disclosed technology relates to methods, background noise suppression systems, and non-transitory computer readable media for background noise suppression. In some examples, frames fragmented from input audio data are projected into a higher dimension space than the input audio data. An estimated speech mask is applied to the frames to separate speech components and noise components of the frames. The speech components are then transformed into a feature domain of the input audio data by performing an inverse projection on the speech components to generate output audio data. The output audio data is provided via an audio interface. The output audio data advantageously comprises a noise-suppressed version of the input audio data.

Abstract: Disclosed are polynucleotides, compositions, and methods related to RNA interference (RNAi). The disclosed polynucleotides, compositions, and methods may be utilized for treating diseases and disorders through RNAi. Particular disclosed are toxic RNAi active seed sequences and methods of using toxic RNAi active sequences for killing cancer cells. The disclosed toxic RNAi active seed sequences preferentially target and inhibit the expression of multiple essential genes for cell survival and/or growth through a process called “death-induced by survival gene elimination” or “DISE.

Abstract: Disclosed are polynucleotides, compositions, and methods related to RNA interference (RNAi). The disclosed polynucleotides, compositions, and methods may be utilized for treating diseases and disorders through RNAi. Particular disclosed are toxic RNAi active seed sequences and methods of using toxic RNAi active sequences for killing cancer cells. The disclosed toxic RNAi active seed sequences preferentially target and inhibit the expression of multiple essential genes for cell survival and/or growth through a process called “death-induced by survival gene elimination” or “DISE.

Abstract: Disclosed are polynucleotides, compositions, and methods related to RNA interference (RNAi). The disclosed polynucleotides, compositions, and methods may be utilized for treating diseases and disorders through RNAi. Particular disclosed are toxic RNAi active seed sequences and methods of using toxic RNAi active sequences for killing cancer cells. The disclosed toxic RNAi active seed sequences preferentially target and inhibit the expression of multiple essential genes for cell survival and/or growth through a process called “death-induced by survival gene elimination” or “DISE.

Abstract: A system and method for providing a purchaser a purchase transaction receipt having a reduced set of information including a transaction identification number, where the transaction identification number can be used by the purchaser to access rebate information and the purchase transaction related information.