Patents by Inventor Monath P. Thomas

Monath P. Thomas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Needleless vaccination using chimeric yellow fever vaccine-vectored vaccines against heterologous flaviviruses
    Publication number: 20040120964
    Abstract: The present invention relates to a method of vaccinating a subject comprising delivering a chimeric yellow fever 17D strain vector expressing an envelope protein gene product of a heterologous flavivirus to the epidermal compartment or the intradermal compartment of the subject's skin. The invention encompasses vaccine compositions comprising the chimeric yellow fever viruses expressing an envelope protein gene product of a heterologous flavivirus. The compositions of the invention result in an enhanced therapeutic efficacy, e.g., enhanced protective immune response as they enhance the presentation and availability of the chimeric vaccine to the targeted compartment of the subject's skin.
    Type: Application
    Filed: October 2, 2003
    Publication date: June 24, 2004
    Inventors: John A. Mikszta, Jason B. Alarcon, Cheryl Dean, Andrea Waterston, Farshad Guirakhoo, Monath P. Thomas