Patents by Inventor Monic Shah

Monic Shah has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS OF PREPARING ICE-BASED LIPID NANOPARTICLES
    Publication number: 20220133631
    Abstract: The present invention provides an improved process for lipid nanoparticle formulation and mRNA encapsulation. In some embodiments, the present invention provides a process of encapsulating messenger RNA (mRNA) in lipid nanoparticles comprising a step of mixing an mRNA solution containing low citrate concentration and a lipid solution at an ambient temperature. Thus, the present invention provides an effective, reliable, energy-saving and cost-effective method of encapsulating mRNA into lipid nanoparticles.
    Type: Application
    Filed: October 12, 2021
    Publication date: May 5, 2022
    Inventors: Monic Shah, Travis Jeanotte, Yi Zhang, Shrirang Karve, Kimberly Gillis, Frank DeRosa
  • PROCESS OF PREPARING MRNA-LOADED LIPID NANOPARTICLES
    Publication number: 20220110884
    Abstract: The present invention provides an improved process for lipid nanoparticle formulation and mRNA encapsulation. In some embodiments, the present invention provides a process of encapsulating messenger RNA (mRNA) in lipid nanoparticles comprising a step of mixing an mRNA solution containing low citrate concentration and a lipid solution at an ambient temperature. Thus, the present invention provides an effective, reliable, energy-saving and cost-effective method of encapsulating mRNA into lipid nanoparticles.
    Type: Application
    Filed: October 12, 2021
    Publication date: April 14, 2022
    Inventors: Shrirang Karve, Travis Jeanotte, Monic Shah, Yi Zhang, Kimberly Gillis, Frank DeRosa