Patents by Inventor Monica Cacho-Izquierdo

Monica Cacho-Izquierdo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Naphthyridin-2 (1 H)-one compounds useful as antibacterials
    Patent number: 8318940
    Abstract: Compounds of Formula (I), wherein substituents R1, R2 and R5 are as defined, and Ar represents substituted phenyl, pyridyl, pyridazinyl, pyrimidinyl, pyrazinyl, thiazolyl, furanyl, imidazolyl and thiophenyl substituted by a hydroxyalkyl substituent and an optional other substituent; compositions containing them, their use in therapy, including their use as antibacterials, for example in the treatment of tuberculosis, and methods for the preparation of such compounds, are provided.
    Type: Grant
    Filed: January 15, 2010
    Date of Patent: November 27, 2012
    Assignee: Glaxo Group Limited
    Inventors: Carlos Alemparte-Gallardo, David Barros-Aguirre, Monica Cacho-Izquierdo, Jose Maria Fiandor Roman, Jose Luis Lavandera Diaz, Modesto Jesús Remuiñan-Blanco
  • NAPHTHYRIDIN-2 (1 H)-ONE COMPOUNDS USEFUL AS ANTIBACTERIALS
    Publication number: 20120115899
    Abstract: Compounds of Formula (I), wherein substituents R1, R2 and R5 are as defined, and Ar represents substituted phenyl, pyridyl, pyridazinyl, pyrimidinyl, pyrazinyl, thiazolyl, furanyl, imidazolyl and thiophenyl substituted by a hydroxyalkyl substituent and an optional other substituent; compositions containing them, their use in therapy, including their use as antibacterials, for example in the treatment of tuberculosis, and methods for the preparation of such compounds, are provided.
    Type: Application
    Filed: January 15, 2010
    Publication date: May 10, 2012
    Inventors: Carlos Alemparte-Gallardo, David Barros-Aguirre, Monica Cacho-Izquierdo, Jose Maria Fiandor Roman, Jose Luis Lavandera Diaz, Modesto Jesús Remuiñan-Blanco
  • Compounds
    Patent number: 8097628
    Abstract: Compounds of Formula (I) or pharmaceutically acceptable salts or N-oxides thereof: (relative chemistry shown) pharmaceutical compositions comprising them, their use in therapy especially against tuberculosis, and methods of preparing them are described.
    Type: Grant
    Filed: May 21, 2009
    Date of Patent: January 17, 2012
    Assignee: Glaxo Group Limited
    Inventors: Carlos Alemparte-Gallardo, Christopher Barfoot, David Barros-Aguirre, Monica Cacho-Izquierdo, Jose Maria Fiandor Roman, Alan Joseph Hennessy, Neil David Pearson, Modesto Jesus Remuinan-Blanco
  • Tricyclic Nitrogen Containing Compounds And Their Use As Antibacterials
    Publication number: 20110071155
    Abstract: Compounds of Formula (I) or pharmaceutically acceptable salts or N-oxides thereof: wherein: one of Z1 and Z2 is CH or N and the other is CH; L is selected from: —CH2—CH?CH—, —CH?CH—CH2—, —(CH2)p— where p is 2, 3 or 4, —CH2—CH2—O—, —O—CH2—CH2—, —CH2—CH2—NH—, —HN—CH2—CH2—, —C(O)—CH?CH—, —CH?CH—C(O)—, —CH2—C?C— or —C?C—CH2—; U represents a cyclic group; m is 0 or 1, n is independently 0 or 1; and substituent(s) R5 and R6 are independently selected from: halo, CF3, OCF3, C1-3 alkyl, C1-3 alkoxy, nitro and cyano, pharmaceurtical compositions comprising them, their use in therapy especially against tuberculosis, and methods of preparing them.
    Type: Application
    Filed: May 20, 2009
    Publication date: March 24, 2011
    Inventors: Carlos Alemparte-Gallardo, David Barros-Aguirre, Monica Cacho-Izquierdo, Jose Maria Fiandor Roman, Modesto Jesus Remuinan-Blanco
  • COMPOUNDS
    Publication number: 20090306089
    Abstract: Compounds of Formula (I) or pharmaceutically acceptable salts or N-oxides thereof: (relative chemistry shown) pharmaceutical compositions comprising them, their use in therapy especially against tuberculosis, and methods of preparing them are described.
    Type: Application
    Filed: May 21, 2009
    Publication date: December 10, 2009
    Inventors: Carlos Alemparte-Gallardo, Christopher Barfoot, David Barros-Aguirre, Monica Cacho-Izquierdo, Jose Maria Fiandor Roman, Alan Joseph Hennessy, Neil David Pearson, Modesto Jesus Remuinan-Blanco