Patents by Inventor Monica Cartelle Gestal

Monica Cartelle Gestal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bordetella vaccine
    Patent number: 11229690
    Abstract: The present invention provides genetically engineered strains of the Bordetella species to include one or more mutations preventing expression of the gene encoding the Bordetella Sigma Regulator (also referred to as “bsr,” “btrS,” and “brpL”), compositions and vaccines thereof, and the use of such engineered strains in methods to protect against Bordetella spp, including but not limited to Bordetella bronchiseptica, B. pertussis, B. parapertussis, B. homelsii, or B. avium. In some aspects, the present invention provides the Bordetella bronchiseptica strain RB50?bsr, compositions and vaccines thereof, and the use of Bordetella bronchiseptica strain RB50?fer in methods to protect against Bordetella spp, including but not limited to Bordetella bronchiseptica, B. pertussis, B. parapertussis, B. homelsii, or B. avium.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: January 25, 2022
    Assignee: UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.
    Inventors: Eric T. Harvill, Monica Cartelle Gestal
  • BORDETELLA VACCINE
    Publication number: 20200222523
    Abstract: The present invention provides genetically engineered strains of the Bordetella species to include one or more mutations preventing expression of the gene encoding the Bordetella Sigma Regulator (also referred to as “bsr,” “btrS,” and “brpL”), compositions and vaccines thereof, and the use of such engineered strains in methods to protect against Bordetella spp, including but not limited to Bordetella bronchiseptica, B. pertussis, B. parapertussis, B. homelsii, or B. avium. In some aspects, the present invention provides the Bordetella bronchiseptica strain RB50?bsr, compositions and vaccines thereof, and the use of Bordetella bronchiseptica strain RB50?fer in methods to protect against Bordetella spp, including but not limited to Bordetella bronchiseptica, B. pertussis, B. parapertussis, B. homelsii, or B. avium.
    Type: Application
    Filed: September 28, 2018
    Publication date: July 16, 2020
    Inventors: Eric T. Harvill, Monica Cartelle Gestal
  • Method for determining DNA fragmentation in microorganisms
    Patent number: 9212391
    Abstract: The present invention relates to a process for determining the DNA integrity in microorganisms and a kit for evaluating the DNA integrity therein. Due to the fact that cell death means DNA fragmentation, with the present process the DNA fragmentation levels in microorganisms can be clearly discriminated in a simple, quick and accurate manner.
    Type: Grant
    Filed: July 23, 2013
    Date of Patent: December 15, 2015
    Assignee: UNIVERSIDAD AUTONOMA DE MADRID
    Inventors: Jaime Gosalvez Berenguer, Jose Luis Fernandez Garcia, Vicente Goyanes Villaescusa, German Bau Arevalo, Lourdes Muriel Rios, Monica Cartelle Gestal
  • Method For Determining DNA Fragmentation In Microorganisms
    Publication number: 20140024031
    Abstract: The present invention relates to a process for determining the DNA integrity in microorganisms and a kit for evaluating the DNA integrity therein. Due to the fact that cell death means DNA fragmentation, with the present process the DNA fragmentation levels in microorganisms can be clearly discriminated in a simple, quick and accurate manner.
    Type: Application
    Filed: July 23, 2013
    Publication date: January 23, 2014
    Applicant: Universidad Autonoma de Madrid
    Inventors: Jaime Gosalvez Berenguer, José Luis Fernandez Garcia, Vicente Goyanes Villaescusa, German Bau Arevalo, Lourdes Muriel Rios, Monica Cartelle Gestal
  • Method for determining DNA fragmentation in microorganisms
    Patent number: 8492086
    Abstract: The invention relates to a method for determining DNA integrity in microorganisms and to a kit for evaluating DNA integrity in same. Since cell death results in DNA fragmentation, the inventive method can be used to determine DNA fragmentation levels in microorganisms clearly, simply, quickly and precisely.
    Type: Grant
    Filed: November 8, 2007
    Date of Patent: July 23, 2013
    Assignee: Universidad Autonoma de Madrid
    Inventors: Jaime Gosalvez Berenguer, José Luis Fernandez Garcia, Vicente Goyanes Villaescusa, German Bau Arevalo, Lourdes Muriel Rios, Monica Cartelle Gestal
  • METHOD FOR DETERMINING DNA FRAGMENTATION IN MICROORGANISMS
    Publication number: 20100129803
    Abstract: The invention relates to a method for determining DNA integrity in microorganisms and to a kit for evaluating DNA integrity in same. Since cell death results in DNA fragmentation, the inventive method can be used to determine DNA fragmentation levels in microorganisms clearly, simply, quickly and precisely.
    Type: Application
    Filed: November 8, 2007
    Publication date: May 27, 2010
    Inventors: Jaime Gosalvez Berenguer, José Luis Fernandez Garcia, Vicente Goyanes Villaescusa, German Bau Arevalo, Lourdes Muriel Rios, Monica Cartelle Gestal