Patents by Inventor Monica Gostissa

Monica Gostissa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • High throughput genome-wide translocation sequencing
    Patent number: 10508304
    Abstract: Provided are methods for high-throughput screening to determine locations of double-stranded DNA breaks (DSBs) and translocations in genomes caused by different agents, such as enzymes.
    Type: Grant
    Filed: October 31, 2016
    Date of Patent: December 17, 2019
    Assignee: CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Frederick W. Alt, Yu Zhang, Roberto Chiarle, Monica Gostissa
  • METHODS AND COMPOSITIONS RELATING TO AN EMBRYONIC STEM CELL-BASED TUMOR MODEL
    Publication number: 20180084766
    Abstract: Provided herein are rapid, reliable methods for generating mice (or other species) that develop tumors of known genotype with respect to two or more mutated, tumor-associated genes using blastocyst complementation.
    Type: Application
    Filed: April 7, 2016
    Publication date: March 29, 2018
    Applicant: THE CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Frederick W. Alt, Feilong Meng, Zhaoqing Ba, Monica Gostissa, Baochun Zhang, Pei-Chi Wei, Bjoern Schwer
  • HIGH THROUGHPUT GENOME-WIDE TRANSLOCATION SEQUENCING
    Publication number: 20170044607
    Abstract: Provided are methods for high-throughput screening to determine locations of double-stranded DNA breaks (DSBs) and translocations in genomes caused by different agents, such as enzymes.
    Type: Application
    Filed: October 31, 2016
    Publication date: February 16, 2017
    Applicant: CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Frederick W. Alt, Yu Zhang, Roberto Chiarle, Monica Gostissa
  • High throughput genome-wide translocation sequencing
    Patent number: 9518293
    Abstract: Provided are methods for high-throughput screening to determine locations of double-stranded DNA breaks (DSBs) and translocations in genomes caused by different agents, such as enzymes.
    Type: Grant
    Filed: July 6, 2012
    Date of Patent: December 13, 2016
    Assignee: Children's Medical Center Corporation
    Inventors: Frederick W. Alt, Zhang Yu, Roberto Chiarle, Monica Gostissa
  • HIGH THROUGHPUT GENOME-WIDE TRANSLOCATION SEQUENCING
    Publication number: 20140234847
    Abstract: Provided are methods for high-throughput screening to determine locations of double-stranded DNA breaks (DSBs) and translocations in genomes caused by different agents, such as enzymes.
    Type: Application
    Filed: July 6, 2012
    Publication date: August 21, 2014
    Inventors: Frederick W. Alt, Yu Zhang, Roberto Chiarle, Monica Gostissa