Patents by Inventor Monica Jo Tomaszewski
Monica Jo Tomaszewski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10393725Abstract: A system and method that images biological samples and uses chromophores to analyze the imaged samples. The chromophore analysis can be done by itself or in conjunction with fluorophore analysis in High Content Imaging systems. To perform chromophore analysis the biological samples can be labeled with different chromophores and imaged using transmitted light that is at least partially absorbed by the chromophores. To also perform fluorophore analysis the samples can also be labeled with fluorophores that are excited by excitation light. The chromophore analysis and fluorophore analysis can be performed separately or concurrently using a High Content Imaging system. The system provides the expanded capability by illuminating the chromophore-labeled samples with transmitted light of different wavelengths and automatically detecting the images which represent the differential absorption of the colored lights by the sample.Type: GrantFiled: January 28, 2019Date of Patent: August 27, 2019Assignee: CELLOMICS, INC.Inventors: Richik Niloy Ghosh, Dirk John VandenBerg, III, Keith Rao Heffley, Monica Jo Tomaszewski, Jeffrey Robert Haskins
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Patent number: 10353130Abstract: An apparatus and method of delivering a precisely sized, homogeneous field of light within an optical system. The apparatus operates equally well over UV, visible, and NIR wavelengths, over a wide range of input beam divergence and regardless of heterogeneity. A tapered or contoured homogenizing rod that creates an evenly distributed illumination at a target area of specific size.Type: GrantFiled: December 8, 2015Date of Patent: July 16, 2019Assignee: Cellomics, Inc.Inventors: Dirk John Vandenberg, Monica Jo Tomaszewski, Keith Rao Heffley, Steven Roland Auger
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Publication number: 20190154652Abstract: A system and method that images biological samples and uses chromophores to analyze the imaged samples. The chromophore analysis can be done by itself or in conjunction with fluorophore analysis in High Content Imaging systems. To perform chromophore analysis the biological samples can be labeled with different chromophores and imaged using transmitted light that is at least partially absorbed by the chromophores. To also perform fluorophore analysis the samples can also be labeled with fluorophores that are excited by excitation light. The chromophore analysis and fluorophore analysis can be performed separately or concurrently using a High Content Imaging system. The system provides the expanded capability by illuminating the chromophore-labeled samples with transmitted light of different wavelengths and automatically detecting the images which represent the differential absorption of the colored lights by the sample.Type: ApplicationFiled: January 28, 2019Publication date: May 23, 2019Inventors: Richik Niloy Ghosh, Dirk John VandenBerg, III, Keith Rao Heffley, Monica Jo Tomaszewski, Jeffrey Robert Haskins
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Patent number: 10234445Abstract: A system and method that images biological samples and uses chromophores to analyze the imaged samples. The chromophore analysis can be done by itself or in conjunction with fluorophore analysis in High Content Imaging systems. To perform chromophore analysis the biological samples can be labeled with different chromophores and imaged using transmitted light that is at least partially absorbed by the chromophores. To also perform fluorophore analysis the samples can also be labeled with fluorophores that are excited by excitation light. The chromophore analysis and fluorophore analysis can be performed separately or concurrently using a High Content Imaging system. The system provides the expanded capability by illuminating the chromophore-labeled samples with transmitted light of different wavelengths and automatically detecting the images which represent the differential absorption of the colored lights by the sample.Type: GrantFiled: May 15, 2017Date of Patent: March 19, 2019Assignee: CELLOMICS, INC.Inventors: Richik Niloy Ghosh, Dirk John VandenBerg, III, Keith Rao Heffley, Monica Jo Tomaszewski, Jeffrey Robert Haskins
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Publication number: 20170276857Abstract: An apparatus and method of delivering a precisely sized, homogeneous field of light within an optical system. The apparatus operates equally well over UV, visible, and NIR wavelengths, over a wide range of input beam divergence and regardless of heterogeneity. A tapered or contoured homogenizing rod that creates an evenly distributed illumination at a target area of specific size.Type: ApplicationFiled: December 8, 2015Publication date: September 28, 2017Applicant: Cellomics, Inc.Inventors: Dirk John VANDENBERG, Monica Jo TOMASZEWSKI, Keith Rao HEFFLEY, Steven Roland AUGER
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Publication number: 20170248574Abstract: A system and method that images biological samples and uses chromophores to analyze the imaged samples. The chromophore analysis can be done by itself or in conjunction with fluorophore analysis in High Content Imaging systems. To perform chromophore analysis the biological samples can be labeled with different chromophores and imaged using transmitted light that is at least partially absorbed by the chromophores. To also perform fluorophore analysis the samples can also be labeled with fluorophores that are excited by excitation light. The chromophore analysis and fluorophore analysis can be performed separately or concurrently using a High Content Imaging system. The system provides the expanded capability by illuminating the chromophore-labeled samples with transmitted light of different wavelengths and automatically detecting the images which represent the differential absorption of the colored lights by the sample.Type: ApplicationFiled: May 15, 2017Publication date: August 31, 2017Inventors: Richik Niloy Ghosh, Dirk John VandenBerg, III, Keith Rao Heffley, Monica Jo Tomaszewski, Jeffrey Robert Haskins
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Patent number: 9683939Abstract: A system and method that images biological samples and uses chromophores to analyze the imaged samples. The chromophore analysis can be done by itself or in conjunction with fluorophore analysis in High Content Imaging systems. To perform chromophore analysis the biological samples can be labeled with different chromophores and imaged using transmitted light that is at least partially absorbed by the chromophores. To also perform fluorophore analysis the samples can also be labeled with fluorophores that are excited by excitation light. The chromophore analysis and fluorophore analysis can be performed separately or concurrently using a High Content Imaging system. The system provides the expanded capability by illuminating the chromophore-labeled samples with transmitted light of different wavelengths and automatically detecting the images which represent the differential absorption of the colored lights by the sample.Type: GrantFiled: May 11, 2015Date of Patent: June 20, 2017Assignee: CELLOMICS, INC.Inventors: Richik Niloy Ghosh, Dirk John VandenBerg, III, Keith Rao Heffley, Monica Jo Tomaszewski, Jeffrey Robert Haskins
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Publication number: 20150323462Abstract: A system and method that images biological samples and uses chromophores to analyze the imaged samples. The chromophore analysis can be done by itself or in conjunction with fluorophore analysis in High Content Imaging systems. To perform chromophore analysis the biological samples can be labeled with different chromophores and imaged using transmitted light that is at least partially absorbed by the chromophores. To also perform fluorophore analysis the samples can also be labeled with fluorophores that are excited by excitation light. The chromophore analysis and fluorophore analysis can be performed separately or concurrently using a High Content Imaging system. The system provides the expanded capability by illuminating the chromophore-labeled samples with transmitted light of different wavelengths and automatically detecting the images which represent the differential absorption of the colored lights by the sample.Type: ApplicationFiled: May 11, 2015Publication date: November 12, 2015Inventors: Richik Niloy Ghosh, Dirk John VandenBerg, III, Keith Rao Heffley, Monica Jo Tomaszewski, Jeffrey Robert Haskins
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Publication number: 20140194321Abstract: A method of predicting whether a compound is a skin sensitizer using an in vitro approach. The method includes a step of imaging immune effector cells positioned within a plurality of containers to obtain imaged cellular targets, each container being treated with a different concentration of a compound. The method further includes a step of quantitatively measuring the imaged cellular targets over a range of concentrations of the compound to detect changes in multiple cellular targets of the immune effector cells associated with skin sensitivity. The method further includes a step of analyzing measurements obtained from the measured imaged cellular targets over the range of concentrations of the compound to determine whether the compound is a skin sensitizer.Type: ApplicationFiled: January 4, 2013Publication date: July 10, 2014Applicant: CELLOMICS, INC.Inventor: Monica Jo Tomaszewski