Patents by Inventor Monica Vaccari

Monica Vaccari has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ras pathways as markers of protection against HIV and methods to improve vaccine efficacy
    Patent number: 10398772
    Abstract: Compositions including a therapeutically effective amount of an HIV immunogen in combination with an agent that stimulates the Ras pathway, wherein the agent is not an aluminum salt, are disclosed. Methods are also disclosed for inducing an immune response to HIV, and/or to inhibit or treat HIV infection, in a subject, using an HIV immunogen and an agent that stimulates the Ras pathway. Methods also are disclosed for determining if an immunogenic composition will induce a protective response, and/or to determine if an immunogenic composition is of use to prevent or treat an HIV infection. The methods including determining if the immunogenic composition increases the level of one or more components of the Ras signaling pathway.
    Type: Grant
    Filed: January 8, 2015
    Date of Patent: September 3, 2019
    Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Services, Oregon Health & Science University
    Inventors: Genoveffa Franchini, Rafick-Pierre Sekaly, Slim Fourati, Mark Cameron, Monica Vaccari, Luca Schifanella, Shari Gordon, Melvin Doster, Namal Malimbada Liyanage
  • RAS PATHWAYS AS MARKERS OF PROTECTION AGAINST HIV AND METHODS TO IMPROVE VACCINE EFFICACY
    Publication number: 20160331830
    Abstract: Compositions including a therapeutically effective amount of an HIV immunogen in combination with an agent that stimulates the Ras pathway, wherein the agent is not an aluminum salt, are disclosed. Methods are also disclosed for inducing an immune response to HIV, and/or to inhibit or treat HIV infection, in a subject, using an HIV immunogen and an agent that stimulates the Ras pathway. Methods also are disclosed for determining if an immunogenic composition will induce a protective response, and/or to determine if an immunogenic composition is of use to prevent or treat an HIV infection. The methods including determining if the immunogenic composition increases the level of one or more components of the Ras signaling pathway.
    Type: Application
    Filed: January 8, 2015
    Publication date: November 17, 2016
    Applicants: THE UNITED STATES OF AMERICA,as represented by the Secretary,Department of Health and Human Services, OREGON HEALTH & SCIENCE UNIVERSITY
    Inventors: Genoveffa Franchini, Rafick-Pierre Sekaly, Slim Fourati, Mark Cameron, Monica Vaccari, Luca Schifanella, Shari Gordon, Melvin Doster, Namal Malimbada Liyanage
  • COMBINED CELL BASED GP96-IG-SIV/HIV, RECOMBINANT GP120 PROTEIN VACCINATION FOR PROTECTION FROM SIV/HIV
    Publication number: 20140286991
    Abstract: Compositions are provided comprising heat shock protein, immunoglobulins and retroviral antigens to induce systemic and mucosal immunity to infection from retroviruses such as Human Immunodeficiency Virus (HIV). Methods of treatment provided comprise administration of the compositions, which boost the immune systems response to the retroviral antigens or immunogens.
    Type: Application
    Filed: February 23, 2012
    Publication date: September 25, 2014
    Applicant: UNIVERSITY OF MIAMI
    Inventors: Eckhard R. Podack, Natasa Strbo, Genoveffa Franchini, Monica Vaccari