Patents by Inventor Monica Van der Vieren

Monica Van der Vieren has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel human beta-2 integrin alpha subunit
    Publication number: 20060280739
    Abstract: Methods to inhibit inflammation and macrophage infiltration following spinal cord injury are disclosed along with methods to modulate TNF? release from cells expressing ?d are disclosed.
    Type: Application
    Filed: February 21, 2006
    Publication date: December 14, 2006
    Applicant: ICOS Corporation
    Inventors: W. Gallatin, Monica Van der Vieren
  • Monoclonal antibodies specific for integrin &agr;-d subunit
    Patent number: 6620915
    Abstract: The present invention relates to monoclonal antibodies immunospecific for &agr;d integrin, and antibodies that compete with said antibodies for &agr;d binding.
    Type: Grant
    Filed: July 8, 1999
    Date of Patent: September 16, 2003
    Assignee: ICOS Corporation
    Inventors: W. Michael Gallatin, Monica Van der Vieren
  • Novel human beta2 integrin alpha subunit
    Publication number: 20030077278
    Abstract: Methods to inhibit inflammation and macrophage infiltration following spinal cord injury are disclosed along with methods to modulate TNF&agr; release from cells expressing &agr;d are disclosed.
    Type: Application
    Filed: June 26, 2001
    Publication date: April 24, 2003
    Applicant: ICOS Corporation
    Inventors: W. Michael Gallatin, Monica Van der Vieren
  • Methods of inhibiting locomotor damage following spinal cord injury with &agr; D-specific antibodies
    Patent number: 6432404
    Abstract: Methods to treat spinal cord injury using &agr;d monoclonal antibodies are disclosed.
    Type: Grant
    Filed: October 13, 2000
    Date of Patent: August 13, 2002
    Assignee: ICOS Corporation
    Inventors: W. Michael Gallatin, Monica Van der Vieren
  • NOVEL HUMAN BETA2 INTEGRIN ALPHA SUBUNIT
    Publication number: 20020062008
    Abstract: Methods to inhibit inflammation and macrophage infiltration following spinal cord injury are disclosed along with methods to modulate TNF&agr; release from cells expressing &agr;d are disclosed.
    Type: Application
    Filed: July 8, 1999
    Publication date: May 23, 2002
    Inventors: W. MICHAEL GALLATIN, MONICA VAN DER VIEREN
  • Methods of inhibiting inflammation at the site of a central nervous system injury with alphaD-specific antibodies
    Patent number: 6251395
    Abstract: Methods to inhibit inflammation and macrophage infiltration following spinal cord injury are disclosed along with methods to modulate TNF&agr; release from cells expressing &agr;d are disclosed.
    Type: Grant
    Filed: November 16, 1998
    Date of Patent: June 26, 2001
    Inventors: W. Michael Gallatin, Monica Van der Vieren
  • Method of identifying modulators of binding between and VCAM-1
    Patent number: 5837478
    Abstract: Methods to identify modulators of .alpha..sub.d binding to VCAM-1 are disclosed.
    Type: Grant
    Filed: October 3, 1997
    Date of Patent: November 17, 1998
    Assignee: ICOS Corporation
    Inventors: W. Michael Gallatin, Monica Van der Vieren
  • Human .beta.2 integrin .alpha. subunit
    Patent number: 5831029
    Abstract: DNA encoding a novel human .beta..sub.2 integrin .alpha. subunit polypeptide, designated .alpha..sub.d, is disclosed along with methods and materials for production of the same by recombinant procedures. Fusion proteins are also disclosed which include extracellular .alpha..sub.d protein fragments, .alpha..sub.d I domain fragments or full length .alpha..sub.d polypeptides and human immunoglobulin constant regions. Binding molecules specific for .alpha..sub.d are also disclosed as useful for modulating the biological activities of .alpha..sub.d. DNA from other species which show homology to human .alpha..sub.d encoding sequences are also disclosed.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: November 3, 1998
    Assignee: ICOS Corporation
    Inventors: W. Michael Gallatin, Monica Van der Vieren
  • Human B2 integrin alpha subunit antibodies
    Patent number: 5817515
    Abstract: Monoclonal antibodies, and hybridomas that express the antibodies, which are immunospecific for a novel human .beta..sub.2 integrin alpha subunit polypeptide are disclosed.
    Type: Grant
    Filed: February 22, 1996
    Date of Patent: October 6, 1998
    Assignee: ICOS Corporation
    Inventors: W. Michael Gallatin, Monica Van der Vieren
  • Human .beta.2 integrin .alpha. subunit
    Patent number: 5766850
    Abstract: DNA encoding a novel human .beta..sub.2 integrin .alpha. subunit polypeptide, designated .alpha..sub.d, is disclosed along with methods and materials for production of the same by recombinant procedures. Fusion proteins are also disclosed which include extracellular .alpha..sub.d protein fragments, .alpha..sub.d I domain fragments or full length .alpha..sub.d polypeptides and human immunoglobulin constant regions. Binding molecules specific for .alpha..sub.d are also disclosed as useful for modulating the biological activities of .alpha..sub.d. DNA from other species which show homology to human .alpha..sub.d encoding sequences are also disclosed.
    Type: Grant
    Filed: December 21, 1994
    Date of Patent: June 16, 1998
    Assignee: ICOS Corporation
    Inventors: W. Michael Gallatin, Monica Van der Vieren
  • Human .beta..sub.2 integrin .alpha.subunit
    Patent number: 5728533
    Abstract: DNA encoding a novel human .beta..sub.2 integrin .alpha. subunit polypeptide, designated .alpha..sub.d, is disclosed along with methods and materials for production of the same by recombinant procedures. Fusion proteins are also disclosed which include extracellular .alpha..sub.d protein fragments, .alpha..sub.d I domain fragments or full length .alpha..sub.d polypeptides and human immunoglobulin constant regions. Binding molecules specific for .alpha..sub.d are also disclosed as useful for modulating the biological activities of .alpha..sub.d. DNA from other species which show homology to human .alpha..sub.d encoding sequences are also disclosed.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: March 17, 1998
    Assignee: ICOS Corporation
    Inventors: W. Michael Gallatin, Monica Van der Vieren
  • Human .beta..sub.2 integrin .alpha. subunit
    Patent number: 5470953
    Abstract: DNA encoding a novel human .beta..sub.2 integrin .alpha. subunit polypeptide, designated .alpha..sub.d, is disclosed along with methods and materials for production of the same by recombinant procedures. Binding molecules specific for .alpha..sub.d are also disclosed as useful for modulating the biological activities of .alpha..sub.d. DNA from other species which show homology to human .alpha..sub.d encoding sequences are also disclosed.
    Type: Grant
    Filed: August 5, 1994
    Date of Patent: November 28, 1995
    Assignee: ICOS Corporation
    Inventors: W. Michael Gallatin, Monica Van der Vieren
  • Human .beta..sub.2 integrin .alpha. subunit
    Patent number: 5437958
    Abstract: DNA encoding a novel human .beta..sub.2 integrin .alpha. subunit polypeptide, designated .alpha..sub.d, is disclosed along with methods and materials for production of the same by recombinant procedures. Binding molecules specific for .alpha..sub.d are also disclosed as useful for modulating the biological activities of .alpha..sub.d.
    Type: Grant
    Filed: December 23, 1993
    Date of Patent: August 1, 1995
    Assignee: ICOS Corporation
    Inventors: William M. Gallatin, Monica Van der Vieren