Patents by Inventor Monika Anna Papworth

Monika Anna Papworth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HETERODIMERIC RELAXIN FUSIONS AND USES THEREOF
    Publication number: 20240025958
    Abstract: The present invention relates to heterodimeric Relaxin fusion polypeptides, in particular to heterodimeric Relaxin 2 fusion polypeptides and uses thereof. Thus, the invention provides Relaxin fusion polypeptides, nucleic acid molecules, vectors, host cells, pharmaceutical compositions and kits comprising the same and uses of the same including methods of treatment. The polypeptides and compositions of the invention may be useful, in particular, in the treatment of cardiovascular diseases, for example for the treatment of heart failure.
    Type: Application
    Filed: July 1, 2023
    Publication date: January 25, 2024
    Inventors: Isabelle SERMADIRAS, Monika Anna PAPWORTH, Judy Christiane PATERSON, Esther Marie MARTIN, Peng KE
  • Heterodimeric Relaxin fusions polypeptides
    Patent number: 11795205
    Abstract: The present invention relates to heterodimeric Relaxin fusion polypeptides, in particular to heterodimeric Relaxin 2 fusion polypeptides and uses thereof. Thus, the invention provides Relaxin fusion polypeptides, nucleic acid molecules, vectors, host cells, pharmaceutical compositions and kits comprising the same and uses of the same including methods of treatment. The polypeptides and compositions of the invention may be useful, in particular, in the treatment of cardiovascular diseases, for example for the treatment of heart failure.
    Type: Grant
    Filed: June 16, 2021
    Date of Patent: October 24, 2023
    Assignee: MEDIMMUNE LIMITED
    Inventors: Isabelle Sermadiras, Monika Anna Papworth, Judy Christiane Paterson, Esther Marie Martin, Peng Ke
  • Heterodimeric Relaxin Fusions and Uses Thereof
    Publication number: 20220017591
    Abstract: The present invention relates to heterodimeric Relaxin fusion polypeptides, in particular to heterodimeric Relaxin 2 fusion polypeptides and uses thereof. Thus, the invention provides Relaxin fusion polypeptides, nucleic acid molecules, vectors, host cells, pharmaceutical compositions and kits comprising the same and uses of the same including methods of treatment. The polypeptides and compositions of the invention may be useful, in particular, in the treatment of cardiovascular diseases, for example for the treatment of heart failure.
    Type: Application
    Filed: June 16, 2021
    Publication date: January 20, 2022
    Inventors: ISABELLE SERMADIRAS, MONIKA ANNA PAPWORTH, JUDY CHRISTIANE PATERSON, ESTHER MARIE MARTIN, PENG KE
  • Modulation of viral gene expression by engineered zinc finger proteins
    Publication number: 20040039175
    Abstract: We disclose a polypeptide capable of binding to a nucleic acid comprising a viral nucleotide sequence. Preferably, the viral nucleotide sequence comprises a viral promoter sequence, for example, an HIV promoter or a herpesvirus promoter sequence.
    Type: Application
    Filed: November 7, 2002
    Publication date: February 26, 2004
    Inventors: Yen Choo, Christophe Demaison, Michael Moore, Monika Anna Papworth, Lindsey Reynolds, Christopher Graeme Ullman, Mark Isalan