Abstract: A negative-working, infrared radiation-sensitive lithographic printing plate precursor is prepared to contain an infrared radiation-sensitive imageable layer that is disposed on the hydrophilic surface of a substrate. This imageable layer contains sufficient free radical chemistry for infrared sensitivity and imaging to polymerize the exposed regions. This chemistry is dispersed within a primary polymeric binder comprising polyalkylenes oxide segments and optional pendant cyano groups and is present in the form of particles, and a secondary crosslinked hydrophobic binder to provide improved ink receptivity, rapid development, and run length especially with aged precursors. Exposed precursors can be developed on-press while forming the first printed impressions.