Patents by Inventor Monika de Arruda Indig

Monika de Arruda Indig has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for detecting target sequences
    Patent number: 6913881
    Abstract: The present invention relates to compositions and methods for the detection and characterization of nucleic acid sequences and variations in nucleic acid sequences. The present invention relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. For example, in some embodiments, a 5? nuclease activity from any of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.
    Type: Grant
    Filed: November 15, 2000
    Date of Patent: July 5, 2005
    Assignee: Third Wave Technologies, Inc.
    Inventors: Brian D. Aizenstein, Eric B. Rasmussen, Jeff G. Hall, Poonam Agarwal, David Arco, Myrta W. Atiles, Deborah E. Burris, Monika de Arruda Indig, Scott M. Law, Andrea L. Mast, David J. Marshall, Carolyn W. Miller, Mary C. Oldenberg, James R. Prudent, Jennifer M. Schneiders, Mary Ann Brow, Victor Lyamichev
  • Characterization of CYP 2D6 genotypes
    Publication number: 20040096874
    Abstract: The present invention provides methods and routines for developing and optimizing nucleic acid detection assays for use in basic research, clinical research, and for the development of clinical detection assays. The present invention also provides cytochrome p450 genotyping methods and reagents for genotyping assays and a genomic DNA copy number assays.
    Type: Application
    Filed: July 10, 2003
    Publication date: May 20, 2004
    Applicant: Third Wave Technologies, Inc.
    Inventors: Matt Neville, Monika de Arruda Indig, Feng Cao, Mary C. Oldenburg, James A. Koelbl, Brian D. Aizenstein, Keith Davey
  • Characterization of CYP 2D6 alleles
    Publication number: 20030235848
    Abstract: The present invention provides methods and routines for developing and optimizing nucleic acid detection assays for use in basic research, clinical research, and for the development of clinical detection assays. The present invention also provides cytochrome p450 genotyping methods and reagents for genotyping assays and a genomic DNA copy number assays.
    Type: Application
    Filed: April 11, 2003
    Publication date: December 25, 2003
    Inventors: Matt Neville, Monika de Arruda Indig
  • Nucleic acid detection in pooled samples
    Publication number: 20030152942
    Abstract: The present invention relates to detecting target nucleic acid sequences in pooled samples. In particular, the present invention relates to compositions and methods for detecting the presence or absence of target nucleic acid sequences (e.g. RNA virus sequences) in a pooled sample employing an INVADER detection assay. In certain embodiments, the present invention allows target nucleic acid sequence detection in pooled biological samples (e.g. pooled blood samples) without prior amplification of the target.
    Type: Application
    Filed: May 9, 2002
    Publication date: August 14, 2003
    Inventors: Lance Fors, Bruce P. Neri, Mary Ann D. Brow, Monika de Arruda Indig, Robert Roeven