Patents by Inventor Monika Lapcikova

Monika Lapcikova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7419709
    Abstract: Coatings are provided in which surfaces may be activated by covalently bonding a silane derivative to the metal surface, covalently bonding a lactone polymer to the silane derivative by in situ ring opening polymerization, and depositing at least one layer of a polyester on the bonded lactone. Biologically active agents may be deposited with the polyester layers. Such coated surfaces may be useful in medical devices, in particular stents.
    Type: Grant
    Filed: November 28, 2006
    Date of Patent: September 2, 2008
    Assignee: CV Therapeutics, Inc.
    Inventors: Frantisek Rypacek, Monika Lapcikova, Ludka Machova
  • Publication number: 20080160166
    Abstract: Coatings are provided in which surfaces may be activated by covalently bonding a silane derivative to the metal surface, covalently bonding a lactone polymer to the silane derivative by in situ ring opening polymerization, and depositing at least one layer of a polyester on the bonded lactone. Biologically active agents may be deposited with the polyester layers. Such coated surfaces may be useful in medical devices, in particular stents.
    Type: Application
    Filed: March 17, 2008
    Publication date: July 3, 2008
    Inventors: Frantisek Rypacek, Monika Lapcikova, Ludka Machova
  • Patent number: 7364768
    Abstract: Coatings are provided in which surfaces may be activated by covalently bonding a silane derivative to the metal surface, covalently bonding a lactone polymer to the silane derivative by in situ ring opening polymerization, and depositing at least one layer of a polyester on the bonded lactone. Biologically active agents may be deposited with the polyester layers. Such coated surfaces may be useful in medical devices, in particular stents.
    Type: Grant
    Filed: November 28, 2006
    Date of Patent: April 29, 2008
    Assignee: CV Therapeutics, Inc.
    Inventors: Frantisek Rypacek, Monika Lapcikova, Ludka Machova
  • Publication number: 20070071926
    Abstract: Coatings are provided in which surfaces may be activated by covalently bonding a silane derivative to the metal surface, covalently bonding a lactone polymer to the silane derivative by in situ ring opening polymerization, and depositing at least one layer of a polyester on the bonded lactone. Biologically active agents may be deposited with the polyester layers. Such coated surfaces may be useful in medical devices, in particular stents.
    Type: Application
    Filed: November 28, 2006
    Publication date: March 29, 2007
    Inventors: Frantisek Rypacek, Monika Lapcikova, Ludka Machova
  • Publication number: 20070071879
    Abstract: Coatings are provided in which surfaces may be activated by covalently bonding a silane derivative to the metal surface, covalently bonding a lactone polymer to the silane derivative by in situ ring opening polymerization, and depositing at least one layer of a polyester on the bonded lactone. Biologically active agents may be deposited with the polyester layers. Such coated surfaces may be useful in medical devices, in particular stents.
    Type: Application
    Filed: November 28, 2006
    Publication date: March 29, 2007
    Inventors: Frantisek Rypacek, Monika Lapcikova, Ludka Machova
  • Patent number: 7160592
    Abstract: Coatings are provided in which surfaces may be activated by covalently bonding a silane derivative to the metal surface, covalently bonding a lactone polymer to the silane derivative by in situ ring opening polymerization, and depositing at least one layer of a polyester on the bonded lactone. Biologically active agents may be deposited with the polyester layers. Such coated surfaces may be useful in medical devices, in particular stents.
    Type: Grant
    Filed: February 14, 2003
    Date of Patent: January 9, 2007
    Assignee: CV Therapeutics, Inc.
    Inventors: Frantisek Rypacek, Monika Lapcikova, Ludka Machova
  • Publication number: 20060093771
    Abstract: Coatings are provided in which surfaces may be activated by covalently bonding a silane derivative to the metal surface, covalently bonding a lactone polymer to the silane derivative by in situ ring opening polymerization, and depositing at least one layer of poly(lactide-co-caprolactone) copolymer on the bonded lactone. Biologically active agents may be disposed with the poly(lactide-co-caprolactone) copolymer layers. Such coated surfaces may be useful in medical devices, in particular stents.
    Type: Application
    Filed: October 14, 2005
    Publication date: May 4, 2006
    Inventors: Frantisek Rypacek, Monika Lapcikova, Ludka Machova
  • Publication number: 20030219562
    Abstract: Coatings are provided in which surfaces may be activated by covalently bonding a silane derivative to the metal surface, covalently bonding a lactone polymer to the silane derivative by in situ ring opening polymerization, and depositing at least one layer of a polyester on the bonded lactone. Biologically active agents may be deposited with the polyester layers. Such coated surfaces may be useful in medical devices, in particular stents.
    Type: Application
    Filed: February 14, 2003
    Publication date: November 27, 2003
    Inventors: Frantisek Rypacek, Monika Lapcikova, Ludka Machova