Patents by Inventor Monika MUELLER

Monika MUELLER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Partial enzymatic hydrolysis of triacylglycerols to produce long-chain polyunsaturated fatty acid
    Patent number: 11535875
    Abstract: Disclosed herein are host cells expressing a polypeptide, wherein the polypeptide hydrolyzes an ester linkage of a triacylglycerol in an oil comprising at least one long-chain polyunsaturated fatty acid, methods for using such host cells, and processes for production of a lipase using such host cells.
    Type: Grant
    Filed: December 29, 2016
    Date of Patent: December 27, 2022
    Assignee: DSM IP ASSETS B.V.
    Inventors: Paul Mugford, Monika Mueller, Martin Schurmann
  • Partial enzymatic hydrolysis of triacylglycerols
    Patent number: 11441099
    Abstract: Disclosed herein are host cells transformed with a nucleic acid molecule comprising a polynucleotide sequence, wherein the polynucleotide sequence encodes a polypeptide that hydrolyzes an ester linkage of a triacylglycerol in an oil comprising at least one long-chain polyunsaturated fatty acid, methods for using such host cells, and processes for production of a lipase using such host cells.
    Type: Grant
    Filed: December 29, 2016
    Date of Patent: September 13, 2022
    Assignee: DSM IP Assets B.V.
    Inventors: Paul Mugford, Monika Mueller, Martin Schurmann
  • PARTIAL ENZYMATIC HYDROLYSIS OF TRIACYLGLYCEROLS
    Publication number: 20210207060
    Abstract: Disclosed herein are host cells transformed with a nucleic acid molecule comprising a polynucleotide sequence, wherein the polynucleotide sequence encodes a polypeptide that hydrolyzes an ester linkage of a triacylglycerol in an oil comprising at least one long-chain polyunsaturated fatty acid, methods for using such host cells, and processes for production of a lipase using such host cells.
    Type: Application
    Filed: December 29, 2016
    Publication date: July 8, 2021
    Inventors: Paul MUGFORD, Monika MUELLER, Martin SCHURMANN
  • PARTIAL ENZYMATIC HYDROLYSIS OF TRIACYLGLYCEROLS
    Publication number: 20210207181
    Abstract: Disclosed herein are host cells expressing a polypeptide, wherein the polypeptide hydrolyzes an ester linkage of a triacylglycerol in an oil comprising at least one long-chain polyunsaturated fatty acid, methods for using such host cells, and processes for production of a lipase using such host cells.
    Type: Application
    Filed: December 29, 2016
    Publication date: July 8, 2021
    Inventors: Paul MUGFORD, Monika MUELLER, Martin SCHURMANN
  • STABILIZATION OF CYTOCHROME P450 REDUCTASE
    Publication number: 20170044556
    Abstract: The present invention relates to a recombinant microorganism which is capable of expressing a cytochrome P450 reductase (CPR) and, optionally, a cytochrome P450 enzyme (CYP) and which is capable of overexpressing a Ice2p comprising the amino acid sequence set out in SEQ ID NO: 2 or a sequence having at least 50% sequence identity thereto. The invention further relates to use of Ice2p to stabilize expression of a cytochrome P450 reductase in a recombinant microorganism.
    Type: Application
    Filed: April 28, 2015
    Publication date: February 16, 2017
    Inventors: Anita EMMERSTORFER, Tamara WRIESSNEGGER, Miriam WIMMER-TEUBENBACHER, Harald PICHLER, Monika MUELLER, Iwona KALUZNA, Martin SCHURMANN
  • CALB muteins and their use
    Patent number: 8206969
    Abstract: A protein having acrylation activity having a polypeptide sequence derived from SEQ ID NO: 1 or NO:2 by introducing at least one of the following amino acid substitutions: L278A, L278V, W104F, T42A, S47A.
    Type: Grant
    Filed: December 18, 2008
    Date of Patent: June 26, 2012
    Assignee: BASF SE
    Inventors: Bernhard Hauer, Cecilia Kvarnström Branneby, Rolf Schmid, Steffen Maurer, Peter Trodler, Danni Liu, Monika Müller
  • New Calb Muteins and Their Use
    Publication number: 20100273223
    Abstract: A protein having acrylation activity having a polypeptide sequence derived from SEQ ID NO: 1 or NO:2 by introducing at least one of the following amino acid substitutions: L278A, L278V, W104F, T42A, S47A.
    Type: Application
    Filed: December 18, 2008
    Publication date: October 28, 2010
    Applicant: BASF SE
    Inventors: Bernhard Hauer, Cecilia Kvarnström Branneby, Rolf Schmid, Steffen Maurer, Peter Trodler, Danni Liu, Monika Müller
  • FUNCTIONAL EXPRESSION OF TRIACYLGYLCEROL LIPASES
    Publication number: 20100151502
    Abstract: The present invention relates to nucleic acids that code for triacylglycerol lipases, vectors comprising said nucleic acids, host cells comprising said nucleic acids or vectors, methods for the expression of triacylglycerol lipases in prokaryotes, methods for the detection and for the production of triacylglycerol lipases, triacylglycerol lipases obtainable thereby, and the use of triacylglycerol lipase-encoding nucleic acids, vectors and recombinant host cells for said methods.
    Type: Application
    Filed: April 5, 2007
    Publication date: June 17, 2010
    Applicant: BASF SE
    Inventors: Bernhard Hauer, Dietmar Häring, Cecilia Kvarnstroem-Branneby, Rolf Schmid, Monika Müller, Danni Liu