Patents by Inventor Monika Rüegsegger

Monika Rüegsegger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibody composition with altered Fab sialylation
    Patent number: 8632773
    Abstract: The present invention relates to a population of antibodies enriched from an antibody preparation, wherein the enriched population of antibodies has an altered amount of sialylation in the Fab region of the antibodies as compared to the antibody preparation prior to enrichment. Furthermore, the present invention relates to a method of enriching a population of antibodies from an antibody preparation, wherein the enriched population of antibodies has an altered amount of sialylation in the Fab region of the antibodies as compared to the antibody preparation prior to enrichment. The present invention also relates to the population of antibodies of the invention for use in medicine, a pharmaceutical composition comprising the populations of antibodies of the invention and the use of the population of antibodies of the invention in the prevention and/or treatment of atherosclerosis, cancer and infections such as bacterial, viral or fungal infections.
    Type: Grant
    Filed: March 26, 2010
    Date of Patent: January 21, 2014
    Assignees: CSL Behring AG, University of Washington
    Inventors: Fabian Käsermann, Monika Rüegsegger, Sylvia Miescher, Keith Elkon
  • ANTIBODY COMPOSITION WITH ALTERED FAB SIALYLATION
    Publication number: 20120009189
    Abstract: The present invention relates to a population of antibodies enriched from an antibody preparation, wherein the enriched population of antibodies has an altered amount of sialylation in the Fab region of the antibodies as compared to the antibody preparation prior to enrichment. Furthermore, the present invention relates to a method of enriching a population of antibodies from an antibody preparation, wherein the enriched population of antibodies has an altered amount of sialylation in the Fab region of the antibodies as compared to the antibody preparation prior to enrichment. The present invention also relates to the population of antibodies of the invention for use in medicine, a pharmaceutical composition comprising the populations of antibodies of the invention and the use of the population of antibodies of the invention in the prevention and/or treatment of atherosclerosis, cancer and infections such as bacterial, viral or fungal infections.
    Type: Application
    Filed: March 26, 2010
    Publication date: January 12, 2012
    Inventors: Fabian Käsermann, Monika Rüegsegger, Sylvia Miescher, Keith Elkon