Patents by Inventor Monika Seller

Monika Seller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Labeling reagent
    Patent number: 7759469
    Abstract: The current invention restates substituted nitroindole nucleosides as both terminal as well as internal building blocks of labeled oligonucleotide probes for the detection, analysis and quantitation of nucleic acids. The substituent comprises a linker and a detectable group or a linker and a reactive group for post synthesis coupling. These modified nucleosides grant access to a wide application area. These new substituted nitroindole nucleosides can be used as labeling reagents for the facile preparation of, e.g., optimized hybridization probes, simple probes, TAQMAN-probes or molecular beacon probes.
    Type: Grant
    Filed: March 8, 2006
    Date of Patent: July 20, 2010
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Dieter Heindl, Thomas Froehlich, Heribert Maerz, Monika Seller
  • Labeling reagent
    Publication number: 20060216736
    Abstract: The current invention restates substituted nitroindole nucleosides as both terminal as well as internal building blocks of labeled oligonucleotide probes for the detection, analysis and quantitation of nucleic acids. The substituent comprises a linker and a detectable group or a linker and a reactive group for post synthesis coupling. These modified nucleosides grant access to a wide application area. These new substituted nitroindole nucleosides can be used as labeling reagents for the facile preparation of, e.g., optimized hybridization probes, simple probes, TAQMAN-probes or molecular beacon probes.
    Type: Application
    Filed: March 8, 2006
    Publication date: September 28, 2006
    Applicant: Roche Diagnostics Opertions, Inc.
    Inventors: Dieter Heindl, Thomas Froehlich, Heribert Maerz, Monika Seller