Patents by Inventor Monika Sharma MELLEM

Monika Sharma MELLEM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11942224
    Abstract: A system for evaluating mental health of patients includes a memory and a control system. The memory contains executable code storing instructions for performing a method. The control system is coupled to the memory and includes one or more processors. The control system is configured to execute the machine executable code to cause the control system to perform the method: A selection of answers associated with a patient is received. The selection of answers corresponds to each question in a series of questions from mental health questionnaires. Unprocessed MRI data are received. The unprocessed MRI data correspond to a set of MRI images of a biological structure associated with the patient. The unprocessed MRI data is processed to output a set of MRI features. Using a machine learning model, the selection of answers and the set of MRI features are processed to output a mental health indication of the patient.
    Type: Grant
    Filed: January 3, 2022
    Date of Patent: March 26, 2024
    Assignee: NEUMORA THERAPEUTICS, INC.
    Inventors: Yuelu Liu, Monika Sharma Mellem, Parvez Ahammad, Humberto Andres Gonzalez Cabezas, Matthew Kollada
  • Publication number: 20230343463
    Abstract: Systems and methods for utilizing machine learning to generate a trans-diagnostic classifier that is operative to concurrently diagnose a plurality of different mental health disorders using a single trans-diagnostic questionnaire that includes a plurality of questions (e.g., 17 questions). Machine learning techniques are used to process labeled training data to build statistical models that include trans-diagnostic item-level questions as features to create a screen to classify groups of subjects as either healthy or as possibly having a mental health disorder. A subset of questions is selected from the multiple self-administered mental health questionnaires and used to autonomously screen subjects across multiple mental health disorders without physician involvement, optionally remotely and repeatedly, in a short amount of time.
    Type: Application
    Filed: May 2, 2023
    Publication date: October 26, 2023
    Inventors: Monika Sharma MELLEM, Yuelu LIU, Parvez AHAMMAD, Humberto Andres GONZALEZ CABEZAS, William J. MARTIN, Pablo Christian GERSBERG
  • Publication number: 20230343461
    Abstract: Systems and methods for utilizing machine learning to generate a trans-diagnostic classifier that is operative to concurrently diagnose a plurality of different mental health disorders using a single trans-diagnostic questionnaire that includes a plurality of questions (e.g., 17 questions). Machine learning techniques are used to process labeled training data to build statistical models that include trans-diagnostic item-level questions as features to create a screen to classify groups of subjects as either healthy or as possibly having a mental health disorder. A subset of questions are selected from the multiple self-administered mental health questionnaires and used to autonomously screen subjects across multiple mental health disorders without physician involvement, optionally remotely and repeatedly, in a short amount of time.
    Type: Application
    Filed: June 14, 2023
    Publication date: October 26, 2023
    Inventors: Monika Sharma MELLEM, Yuelu Liu, Parvez Ahammad, Humberto Andres Gonzalez Cabezas, William J. Martin, Pablo Christian Gersberg
  • Patent number: 11715564
    Abstract: Systems and methods for utilizing machine learning to generate a trans-diagnostic classifier that is operative to concurrently diagnose a plurality of different mental health disorders using a single trans-diagnostic questionnaire that includes a plurality of questions (e.g., 17 questions). Machine learning techniques are used to process labeled training data to build statistical models that include trans-diagnostic item-level questions as features to create a screen to classify groups of subjects as either healthy or as possibly having a mental health disorder. A subset of questions are selected from the multiple self-administered mental health questionnaires and used to autonomously screen subjects across multiple mental health disorders without physician involvement, optionally remotely and repeatedly, in a short amount of time.
    Type: Grant
    Filed: May 1, 2019
    Date of Patent: August 1, 2023
    Assignee: NEUMORA THERAPEUTICS, INC.
    Inventors: Monika Sharma Mellem, Yuelu Liu, Parvez Ahammad, Humberto Andres Gonzalez Cabezas, William J. Martin, Pablo Christian Gersberg
  • Patent number: 11676732
    Abstract: Systems and methods for utilizing machine learning to generate a trans-diagnostic classifier that is operative to concurrently diagnose a plurality of different mental health disorders using a single trans-diagnostic questionnaire that includes a plurality of questions (e.g., 17 questions). Machine learning techniques are used to process labeled training data to build statistical models that include trans-diagnostic item-level questions as features to create a screen to classify groups of subjects as either healthy or as possibly having a mental health disorder. A subset of questions is selected from the multiple self-administered mental health questionnaires and used to autonomously screen subjects across multiple mental health disorders without physician involvement, optionally remotely and repeatedly, in a short amount of time.
    Type: Grant
    Filed: September 1, 2021
    Date of Patent: June 13, 2023
    Assignee: NEUMORA THERAPEUTICS, INC.
    Inventors: Monika Sharma Mellem, Yuelu Liu, Parvez Ahammad, Humberto Andres Gonzalez Cabezas, William J. Martin, Pablo Christian Gersberg
  • Publication number: 20220172822
    Abstract: The method for evaluating mental health of a patient includes displaying a series of inquiries from mental health questionnaires on a display device. Each inquiry of the series of inquiries includes text and a set of answers. A series of selections is received from a user interface. Each selection of the series of selections is representative of an answer of the set of answers for each corresponding inquiry in the series of inquiries. Unprocessed MRI data are received. The unprocessed MRI data correspond to a set of MRI images of a biological structure associated with a patient. Using a machine learning model, the series of selections and the unprocessed MRI data are processed. The series of selections being processed corresponds to the series of inquiries. A symptom severity indicator for a mental health category of the patient is outputted.
    Type: Application
    Filed: February 18, 2022
    Publication date: June 2, 2022
    Inventors: Monika Sharma Mellem, Yuelu Liu, Parvez Ahammad, Humberto Andres Gonzalez Cabezas, Matthew Kollada
  • Publication number: 20220139560
    Abstract: A system for evaluating mental health of patients includes a memory and a control system. The memory contains executable code storing instructions for performing a method. The control system is coupled to the memory and includes one or more processors. The control system is configured to execute the machine executable code to cause the control system to perform the method: A selection of answers associated with a patient is received. The selection of answers corresponds to each question in a series of questions from mental health questionnaires. Unprocessed MRI data are received. The unprocessed MRI data correspond to a set of MRI images of a biological structure associated with the patient. The unprocessed MRI data is processed to output a set of MRI features. Using a machine learning model, the selection of answers and the set of MRI features are processed to output a mental health indication of the patient.
    Type: Application
    Filed: January 3, 2022
    Publication date: May 5, 2022
    Inventors: Yuelu Liu, Monika Sharma Mellem, Parvez Ahammad, Humberto Andres Gonzalez Cabezas, Matthew Kollada
  • Publication number: 20220139530
    Abstract: The present disclosure provides systems and methods for automating the QC of MRI scans. Particularly, the inventors trained machine learning classifiers using features derived from brain MR images and associated processing to predict the quality of those images, which is based on the ground truth of an expert's opinion. In one example, classifiers that utilized features derived from preprocessing log files (textual files output during MRI preprocessing) were particularly accurate and demonstrated an ability to be generalized to new datasets, which allows the disclosed technology to be scalable to new datasets and MRI preprocessing pipelines.
    Type: Application
    Filed: April 21, 2020
    Publication date: May 5, 2022
    Inventors: Matthew KOLLADA, Humberto Andres GONZALEZ CABEZAS, Yuelu LIU, Monika Sharma MELLEM, Parvez AHAMMAD, Qingzhu GAO
  • Patent number: 11289187
    Abstract: The method for evaluating mental health of a patient includes displaying a series of inquiries from mental health questionnaires on a display device. Each inquiry of the series of inquiries includes text and a set of answers. A series of selections is received from a user interface. Each selection of the series of selections is representative of an answer of the set of answers for each corresponding inquiry in the series of inquiries. Unprocessed MRI data are received. The unprocessed MRI data correspond to a set of MRI images of a biological structure associated with a patient. Using a machine learning model, the series of selections and the unprocessed MRI data are processed. The series of selections being processed corresponds to the series of inquiries. A symptom severity indicator for a mental health category of the patient is outputted.
    Type: Grant
    Filed: August 29, 2019
    Date of Patent: March 29, 2022
    Assignee: BLACKTHORN THERAPEUTICS, INC.
    Inventors: Monika Sharma Mellem, Yuelu Liu, Parvez Ahammad, Humberto Andres Gonzalez Cabezas, Matthew Kollada
  • Patent number: 11244762
    Abstract: A system for evaluating mental health of patients includes a memory and a control system. The memory contains executable code storing instructions for performing a method. The control system is coupled to the memory and includes one or more processors. The control system is configured to execute the machine executable code to cause the control system to perform the method: A selection of answers associated with a patient is received. The selection of answers corresponds to each question in a series of questions from mental health questionnaires. Unprocessed MRI data are received. The unprocessed MRI data correspond to a set of MRI images of a biological structure associated with the patient. The unprocessed MRI data is processed to output a set of MRI features. Using a machine learning model, the selection of answers and the set of MRI features are processed to output a mental health indication of the patient.
    Type: Grant
    Filed: August 29, 2019
    Date of Patent: February 8, 2022
    Assignee: BLACKTHORN THERAPEUTICS, INC.
    Inventors: Yuelu Liu, Monika Sharma Mellem, Parvez Ahammad, Humberto Andres Gonzalez Cabezas, Matthew Kollada
  • Publication number: 20210398685
    Abstract: Systems and methods for utilizing machine learning to generate a trans-diagnostic classifier that is operative to concurrently diagnose a plurality of different mental health disorders using a single trans-diagnostic questionnaire that includes a plurality of questions (e.g., 17 questions). Machine learning techniques are used to process labeled training data to build statistical models that include trans-diagnostic item-level questions as features to create a screen to classify groups of subjects as either healthy or as possibly having a mental health disorder. A subset of questions is selected from the multiple self-administered mental health questionnaires and used to autonomously screen subjects across multiple mental health disorders without physician involvement, optionally remotely and repeatedly, in a short amount of time.
    Type: Application
    Filed: September 1, 2021
    Publication date: December 23, 2021
    Inventors: Monika Sharma MELLEM, Yuelu LIU, Parvez AHAMMAD, Humberto Andres GONZALEZ CABEZAS, William J. MARTIN, Pablo Christian GERSBERG
  • Publication number: 20210358594
    Abstract: The method for evaluating mental health of a patient includes displaying a series of inquiries from mental health questionnaires on a display device. Each inquiry of the series of inquiries includes text and a set of answers. A series of selections is received from a user interface. Each selection of the series of selections is representative of an answer of the set of answers for each corresponding inquiry in the series of inquiries. Unprocessed MRI data are received. The unprocessed MRI data correspond to a set of MRI images of a biological structure associated with a patient. Using a machine learning model, the series of selections and the unprocessed MRI data are processed. The series of selections being processed corresponds to the series of inquiries. A symptom severity indicator for a mental health category of the patient is outputted.
    Type: Application
    Filed: August 29, 2019
    Publication date: November 18, 2021
    Inventors: Monika Sharma Mellem, Yuelu Liu, Parvez Ahammad, Humberto Andres Gonzalez Cabezas, Matthew Kollada
  • Publication number: 20210319899
    Abstract: A system for evaluating mental health of patients includes a memory and a control system. The memory contains executable code storing instructions for performing a method. The control system is coupled to the memory and includes one or more processors. The control system is configured to execute the machine executable code to cause the control system to perform the method: A selection of answers associated with a patient is received. The selection of answers corresponds to each question in a series of questions from mental health questionnaires. Unprocessed MM data are received. The unprocessed MRI data correspond to a set of MM images of a biological structure associated with the patient. The unprocessed MRI data is processed to output a set of MRI features. Using a machine learning model, the selection of answers and the set of MRI features are processed to output a mental health indication of the patient.
    Type: Application
    Filed: August 29, 2019
    Publication date: October 14, 2021
    Inventors: Yuelu Liu, Monika Sharma Mellem, Parvez Ahammad, Humberto Andres Gonzalez Cabezas, Matthew Kollada
  • Patent number: 11139083
    Abstract: Systems and methods for utilizing machine learning to generate a trans-diagnostic classifier that is operative to concurrently diagnose a plurality of different mental health disorders using a single trans-diagnostic questionnaire that includes a plurality of questions (e.g., 17 questions). Machine learning techniques are used to process labeled training data to build statistical models that include trans-diagnostic item-level questions as features to create a screen to classify groups of subjects as either healthy or as possibly having a mental health disorder. A subset of questions are selected from the multiple self-administered mental health questionnaires and used to autonomously screen subjects across multiple mental health disorders without physician involvement, optionally remotely and repeatedly, in a short amount of time.
    Type: Grant
    Filed: July 17, 2019
    Date of Patent: October 5, 2021
    Assignee: BlackThorn Therapeutics, Inc.
    Inventors: Monika Sharma Mellem, Yuelu Liu, Parvez Ahammad, Humberto Andres Gonzalez Cabezas, William J. Martin, Pablo Christian Gersberg
  • Publication number: 20190355474
    Abstract: Systems and methods for utilizing machine learning to generate a trans-diagnostic classifier that is operative to concurrently diagnose a plurality of different mental health disorders using a single trans-diagnostic questionnaire that includes a plurality of questions (e.g., 17 questions). Machine learning techniques are used to process labeled training data to build statistical models that include trans-diagnostic item-level questions as features to create a screen to classify groups of subjects as either healthy or as possibly having a mental health disorder. A subset of questions are selected from the multiple self-administered mental health questionnaires and used to autonomously screen subjects across multiple mental health disorders without physician involvement, optionally remotely and repeatedly, in a short amount of time.
    Type: Application
    Filed: July 17, 2019
    Publication date: November 21, 2019
    Applicant: BlackThorn Therapeutics, Inc.
    Inventors: Monika Sharma MELLEM, Yuelu LIU, Parvez AHAMMAD, Humberto Andres GONZALEZ CABEZAS, William J. MARTIN, Pablo Christian GERSBERG