Patents by Inventor Monique Gastineau

Monique Gastineau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use Of An Antagonist Of Epac For Treating Human Cardiac Hypertrophy
    Publication number: 20090169540
    Abstract: The present invention relates to the use of at least one Epac (Exchange Protein directly Activated by cAMP) antagonist for the manufacture of a medicament intended for the prevention or the treatment of pathologies selected from the list comprising cardiac hypertrophy, cardiac arrhythmias, valvulopathies, diastolic dysfunction, chronic heart failure, ischemic heart failure, and myocarditis.
    Type: Application
    Filed: March 2, 2006
    Publication date: July 2, 2009
    Applicant: INSERM (Institute National De La Sane Et De La Recherche Medicle)
    Inventors: Frank Lezoualc'h, Eric Morel, Monique Gastineau, Gregoire Vandecasteele
  • Splice variants for human 5-HT4 serotonin receptor and their applications, in particular for screening
    Patent number: 6506580
    Abstract: The invention concerns an isolated polypeptide constitutive of splice variants for human serotonin receptor whereof the amino acid sequence is selected among the sequence SEQ ID No. 2 of the 5-HT4(c) polypeptide variant or the sequence SEQ ID No. 4 of the 5-HT4(d) polypeptide variant, or any polypeptide fragment or biologically active derivative thereof. The invention also concerns the inverse agonist effect of ML 10375 on 5-HT4(c) and 5-HT4(d) receptors.
    Type: Grant
    Filed: September 19, 2000
    Date of Patent: January 14, 2003
    Assignee: Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Rodolphe Fischmeister, Michel Langlois, Yamina Dahmoune, Monique Gastineau, Olivier Blondel, Johan Hoebeke