Patents by Inventor Monique LaRae HOWARD

Monique LaRae HOWARD has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160032014
    Abstract: The present invention provides compositions and methods relating to or derived from antigen binding proteins capable of inhibiting PCSK9 binding to LDLR and having increased pH sensitivity, improved binding affinity and/or increased in vivos half life. In embodiments, the antigen binding proteins specifically bind PCSK9 and have increased pH sensitivity, improved binding affinity and/or increased in vivos half life.
    Type: Application
    Filed: March 14, 2014
    Publication date: February 4, 2016
    Applicant: AMGEN INC.
    Inventors: Mark Leo MICHAELS, Randal R. KETCHEM, Derek E. PIPER, Wei YAN, Chadwick Terence KING, Monique LaRae HOWARD