Patents by Inventor Monique van Hoek

Monique van Hoek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230074829
    Abstract: Provided is an engineered antimicrobial peptide. Also provided is a composition comprising an engineered antimicrobial peptide. Provided is a method of treating a subject in need thereof, comprising administering a therapeutically effective amount of a composition comprising an engineered antimicrobial peptide. Also provided is a method of producing an engineered antimicrobial peptide.
    Type: Application
    Filed: August 25, 2022
    Publication date: March 9, 2023
    Applicant: GEORGE MASON UNIVERSITY
    Inventors: SHRAVANI BOBDE, MONIQUE VAN HOEK
  • Patent number: 11180528
    Abstract: Peptides are described herein, in particular peptides having antimicrobial properties, as are compositions, articles, and kits comprising such peptides, and methods for using the peptides.
    Type: Grant
    Filed: November 26, 2019
    Date of Patent: November 23, 2021
    Assignee: George Mason University
    Inventors: Barney Bishop, Monique Van Hoek, Stephanie Barksdale
  • Publication number: 20200172570
    Abstract: Peptides are described herein, in particular peptides having antimicrobial properties, as are compositions, articles, and kits comprising such peptides, and methods for using the peptides.
    Type: Application
    Filed: November 26, 2019
    Publication date: June 4, 2020
    Applicant: George Mason University
    Inventors: Barney BISHOP, Monique VAN HOEK, Stephanie BARKSDALE
  • Patent number: 10633420
    Abstract: Peptides having antimicrobial properties are described herein, as are compositions containing such peptides, and methods for using the peptides.
    Type: Grant
    Filed: July 27, 2017
    Date of Patent: April 28, 2020
    Assignee: GEORGE MASON RESEARCH FOUNDATION, INC.
    Inventors: Barney Bishop, Monique van Hoek, Ezra Myung Chul Chung
  • Publication number: 20190352337
    Abstract: Peptides having antimicrobial properties are described herein, as are compositions containing such peptides, and methods for using the peptides.
    Type: Application
    Filed: July 27, 2017
    Publication date: November 21, 2019
    Applicant: George Mason Research Foundation, Inc.
    Inventors: Barney Bishop, Monique van Hoek, Ezra Myung Chul Chung
  • Patent number: 10174081
    Abstract: Materials and methods for making and using cationic anti-microbial peptides (CAMPs), and compositions containing such peptides.
    Type: Grant
    Filed: April 20, 2012
    Date of Patent: January 8, 2019
    Assignee: George Mason Research Foundation, Inc.
    Inventors: Barney Bishop, Monique van Hoek
  • Patent number: 9849189
    Abstract: A cationic antimicrobial peptide (CAMP) conjugate is disclosed. The CAMP conjugate may be made by identifying a suitable carrier peptide; identifying a suitable antimicrobial agent; creating a conjugate by conjugating the peptide with the antimicrobial agent; and evaluating and refining the conjugate. The peptide may be short peptide based on the sequence of a CAMP, such as human ?-defensin-3. The peptide can be directly connected to the antimicrobial agent or through a linker segment. The antimicrobial agent may be connected to the peptide or the linker segment through stable or cleavable bonding. The peptide may carry and facilitate the delivery of the conjugated antimicrobial agent to a microbe.
    Type: Grant
    Filed: May 2, 2016
    Date of Patent: December 26, 2017
    Assignee: George Mason Research Foundation, Inc.
    Inventors: Barney Bishop, Monique van Hoek, Keith M. Davies
  • Publication number: 20160367692
    Abstract: A cationic antimicrobial peptide (CAMP) conjugate is disclosed. The CAMP conjugate may be made by identifying a suitable carrier peptide; identifying a suitable antimicrobial agent; creating a conjugate by conjugating the peptide with the antimicrobial agent; and evaluating and refining the conjugate. The peptide may be short peptide based on the sequence of a CAMP, such as human ?-defensin-3. The peptide can be directly connected to the antimicrobial agent or through a linker segment. The antimicrobial agent may be connected to the peptide or the linker segment through stable or cleavable bonding. The peptide may carry and facilitate the delivery of the conjugated antimicrobial agent to a microbe.
    Type: Application
    Filed: May 2, 2016
    Publication date: December 22, 2016
    Inventors: Barney Bishop, Monique van Hoek, Keith M. Davies
  • Publication number: 20140128313
    Abstract: Materials and methods for making and using cationic anti-microbial peptides (CAMPs), and compositions containing such peptides.
    Type: Application
    Filed: April 20, 2012
    Publication date: May 8, 2014
    Inventors: Barney Bishop, Monique van Hoek
  • Patent number: 8404636
    Abstract: A cationic antimicrobial peptide (CAMP) conjugate is disclosed. The CAMP conjugate may be made by identifying a suitable carrier peptide; identifying a suitable antimicrobial agent; creating a conjugate by conjugating the peptide with the antimicrobial agent; and evaluating and refining the conjugate. The peptide may be short peptide based on the sequence of a CAMP, such as human ?-defensin-3. The peptide can be directly connected to the antimicrobial agent or through a linker segment. The antimicrobial agent may be connected to the peptide or the linker segment through stable or cleavable bonding. The peptide may carry and facilitate the delivery of the conjugated antimicrobial agent to a microbe.
    Type: Grant
    Filed: July 14, 2009
    Date of Patent: March 26, 2013
    Assignee: George Mason Intellectual Properties, Inc.
    Inventors: Barney Bishop, Monique van Hoek, Keith M. Davies
  • Publication number: 20120288860
    Abstract: Disclosed herein are methods, constructs, kits, and the like, which can be used for detecting and/or differentiating interstitial lung disease. For example, idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP) can be detected and/or differentiated using at least one biomarker.
    Type: Application
    Filed: May 11, 2012
    Publication date: November 15, 2012
    Inventors: MONIQUE VAN HOEK, STEVEN NATHAN
  • Publication number: 20120149631
    Abstract: The present disclosure relates to peptides, and fragments thereof, conferring antimicrobial and/or antibiofilm growth, as well as products and methodology for using same.
    Type: Application
    Filed: June 16, 2010
    Publication date: June 14, 2012
    Inventors: Frank Delatour, Monique Van Hoek, Barney Bishop
  • Publication number: 20100022750
    Abstract: A cationic antimicrobial peptide (CAMP) conjugate is disclosed. The CAMP conjugate may be made by identifying a suitable carrier peptide; identifying a suitable antimicrobial agent; creating a conjugate by conjugating the peptide with the antimicrobial agent; and evaluating and refining the conjugate. The peptide may be short peptide based on the sequence of a CAMP, such as human ?-defensin-3. The peptide can be directly connected to the antimicrobial agent or through a linker segment. The antimicrobial agent may be connected to the peptide or the linker segment through stable or cleavable bonding. The peptide may carry and facilitate the delivery of the conjugated antimicrobial agent to a microbe.
    Type: Application
    Filed: July 14, 2009
    Publication date: January 28, 2010
    Inventors: Barney Bishop, Monique van Hoek, Keith M. Davies