Patents by Inventor Monkol LEK

Monkol LEK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR UPREGULATING ISOFORMS OF DYSTROPHIN AS THERAPY FOR DUCHENNE MUSCULAR DYSTROPHY (DMD)
    Publication number: 20240091379
    Abstract: The present invention includes methods for treating a disease or disorder that is associated with aberrant or absent dystrophin, by upregulating a brain isoform of dystrophin (e.g. purkinje and/or cortical) in a subject in need thereof. The method comprises administering to the subject a composition that upregulates a brain isoform of dystrophin.
    Type: Application
    Filed: October 9, 2020
    Publication date: March 21, 2024
    Inventors: Monkol LEK, Angela LEK, Keryn WOODMAN, Kaiyue MA
  • Diagnosing COL6-related disorders and methods for treating same
    Patent number: 11655470
    Abstract: A single nucleotide polymorphism (SNP) that results in development of a Type VI collagen, alpha 1 chain-related disorder, and the use of the SNP to identify individuals at risk for developing COL6-related disorders (COL6-RD). Also provided are antisense oligomers for treating individuals at risk for developing COL6-RD, as well as methods for screening compounds for their potential as therapeutic agents.
    Type: Grant
    Filed: July 5, 2017
    Date of Patent: May 23, 2023
    Assignee: The USA, as represented by the Secretary, Dept. of Health and Human Services
    Inventors: Carsten G. Bonnemann, Veronique Bolduc, Francesco Muntoni, Steve Wilton, Daniel Macarthur, Monkol Lek, Beryl Cummings
  • DIAGNOSING COL6-RELATED DISORDERS AND METHODS FOR TREATING SAME
    Publication number: 20190367917
    Abstract: A single nucleotide polymorphism (SNP) that results in development of a Type VI collagen, alpha 1 chain-related disorder, and the use of the SNP to identify individuals at risk for developing COL6-related disorders (COL6-RD). Also provided are antisense oligomers for treating individuals at risk for developing COL6-RD, as well as methods for screening compounds for their potential as therapeutic agents.
    Type: Application
    Filed: July 5, 2017
    Publication date: December 5, 2019
    Inventors: Carsten G. BONNEMANN, Veronique BOLDUC, Francesco MUNTONI, Steve WILTON, Daniel MACARTHUR, Monkol LEK, Beryl CUMMINGS