Patents by Inventor Monsif BOUABOULA

Monsif BOUABOULA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF AS ANTICANCER DRUGS
    Publication number: 20120053170
    Abstract: The present invention relates to nicotinamide derivatives of formula (I), to compositions containing same, and to the therapeutic use thereof, in particular as anticancer drugs. The invention also relates to the method for preparing said compounds, as well as to some of the intermediate products.
    Type: Application
    Filed: March 22, 2010
    Publication date: March 1, 2012
    Applicant: SANOFI
    Inventors: Jérome Arigon, Claude Bernhart, Monsif Bouaboula, Romain Combet, Sandrine Hilairet, Samir Jegham
  • ANTINEOPLASTIC DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF
    Publication number: 20110251194
    Abstract: The disclosure concerns heterobicyclic compounds of general formula (I) and acid addition salts, hydrates and solvates thereof, as well as enantiomers, diastereoisomers and mixtures thereof. Methods for preparing the compounds, pharmaceutical compositions, and methods of treatment also are disclosed.
    Type: Application
    Filed: January 7, 2011
    Publication date: October 13, 2011
    Applicant: SANOFI-AVENTIS
    Inventors: Claude BERNHART, Gary MCCORT, Samir JEGHAM, Jean Marc HERBERT, Pierre CASELLAS, Monsif BOUABOULA, Olivier DUCLOS
  • NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF
    Publication number: 20100222319
    Abstract: The disclosure relates to compounds of formula (I): wherein A, Z, Z?, L, R2 and R3 are as defined in the disclosure, to compositions comprising said compounds, and to methods for the manufacture and therapeutic use thereof.
    Type: Application
    Filed: March 26, 2010
    Publication date: September 2, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Claude BERNHART, Monsif BOUABOULA, Pierre CASELLAS, Samir JEGHAM, Jèrome ARIGON, Romain COMBET, Sandrine HILAIRET, Pierre FRAISSE
  • 2-ANILINO-4-HETEROARYL PYRIMIDINE DERIVATIVES, AND PREPARATION THEREOF AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS, AND IN PARTICULAR IKK INHIBITORS
    Publication number: 20100099694
    Abstract: The disclosure relates to a compound of formula (I): wherein R, R2, R3, R4, R5, z, D and W are as defined in the specification, to compositions containing them, to processes for preparing them, and to their use in the treatment or prevention of conditions capable of being modulated by the inhibition of the activity of protein kinases.
    Type: Application
    Filed: July 1, 2009
    Publication date: April 22, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Didier BABIN, Monsif BOUABOULA, Pierre CASELLAS, Serge MIGNANI, Jean-Flaubert NGUEFACK, Jean WAGNON
  • N,N'-2,4-DIANILINOPYRIMIDINE DERIVATIVES, PREPARATION THEREOF AS DRUGS, PHARMACEUTICAL COMPOSITIONS ESSENTIALLY AS IKK INHIBITORS
    Publication number: 20100093668
    Abstract: The disclosure relates to a compound of formula (I): wherein R, R1, R2, R3, R4, R5, R6 and Z are as defined in the specification, to compositions containing them, to processes for preparing them, and to their use in the treatment or prevention of conditions capable of being modulated by the inhibition of the activity of protein kinases.
    Type: Application
    Filed: July 1, 2009
    Publication date: April 15, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Didier BABIN, Monsif BOUABOULA, Pierre CASELLAS, Maria MENDEZ-PEREZ, Serge MIGNANI, Jean-Flaubert NGUEFACK, Jacob-Alsboek OLSEN, Bernard TONNERRE, Jean WAGNON
  • NOVEL PHENYL(4-PHENYLPYRIMIDIN-2-YL)AMINE DERIVATIVES, THEIR PREPARATION, AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND IN PARTICULAR AS IKK INHIBITORS
    Publication number: 20100069417
    Abstract: The disclosure relates to a compound of formula (I): wherein R, R2, R3, R4, R5, Z, W and D are as defined in the specification, to compositions containing them, to processes for preparing them, and to their use in the treatment or prevention of conditions capable of being modulated by the inhibition of the activity of protein kinases.
    Type: Application
    Filed: July 1, 2009
    Publication date: March 18, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Monsif BOUABOULA, Pierre CASELLAS, Sherri DUDAL, Regine FLOUTARD, Maria MENDEZ-PEREZ, Jean-Flaubert NGUEFACK, Jacob-Alsboek OLSEN, Bernard TONNERRE, Jean WAGNON
  • NEW 2,4-DIANILINOPYRIMIDINES, PREPARATION THEREOF AS DRUGS, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF ESSENTIALLY AS IKK INHIBITORS
    Publication number: 20100035907
    Abstract: The disclosure relates to a compound of formula (I): wherein R1, R2, R3, R4, R5, A and Y are as defined in the specification, to compositions containing them, to processes for preparing them, and to their use in the treatment or prevention of conditions capable of being modulated by the inhibition of the activity of protein kinases.
    Type: Application
    Filed: July 1, 2009
    Publication date: February 11, 2010
    Applicant: Sanofi-aventis
    Inventors: Monsif BOUABOULA, Michael BOSCH, Pierre CASELLAS, Jean-Flaubert Nguefack, Bernard Tonnerre, Jean Wagnon
  • Novel 2,4-Dianilinopyrimidine Derivatives, the Preparation Thereof, Their Use as Medicaments, Pharmaceutical Compositions and, in Particular, as IKK Inhibitors
    Publication number: 20080269170
    Abstract: The disclosure relates to compounds of formula (I): wherein R1-R5, A and Y are as defined in the disclosure, to compositions comprising said compounds, and to processes for making and methods of using the same.
    Type: Application
    Filed: January 9, 2008
    Publication date: October 30, 2008
    Applicant: sanofi-aventis
    Inventors: Michael Bosch, Monsif Bouaboula, Pierre Casellas, Samir Jegham, Serge Mignani, Jean-Flaubert Nguefack, Jacob-Alsboek Olsen, Bernard Tonnerre, Jean Wagnon